Phenotype shift from atypical scrapie to CH1641 following experimental transmission in sheep.
The interactions of host and infecting strain in ovine transmissible spongiform encephalopathies are known to be complex, and have a profound effect on the resulting phenotype of disease. In contrast to classical scrapie, the pathology in naturally-occurring cases of atypical scrapie appears more co...
Main Authors: | Marion M Simmons, S Jo Moore, Richard Lockey, Melanie J Chaplin, Timm Konold, Christopher Vickery, John Spiropoulos |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0117063 |
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