Assessment and Correlation of Salivary Ca, Mg, and pH in Smokers and Non-Smokers with Generalized Chronic Periodontitis
<i>Background and Objectives</i>: Diagnostic evaluation with the aid of biomarkers has reached newer heights to assess disease activity. Salivary calcium, magnesium, and pH are one of the biochemical parameters which can be helpful in assessing the progression of periodontal disease. Smo...
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| Format: | Article |
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MDPI AG
2023-04-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/59/4/765 |
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| author | Saad Mohammad Alqahtani Shankar T. Gokhale Mohamed Fadul A. Elagib Deepti Shrivastava Raghavendra Reddy Nagate Badar Awadh Mohammad Alshmrani Abduaziz Mohammed Abdullah Alburade Fares Mufreh Abdullah Alqahtani Anil Kumar Nagarajappa Valentino Natoli Kumar Chandan Srivastava |
| author_facet | Saad Mohammad Alqahtani Shankar T. Gokhale Mohamed Fadul A. Elagib Deepti Shrivastava Raghavendra Reddy Nagate Badar Awadh Mohammad Alshmrani Abduaziz Mohammed Abdullah Alburade Fares Mufreh Abdullah Alqahtani Anil Kumar Nagarajappa Valentino Natoli Kumar Chandan Srivastava |
| author_sort | Saad Mohammad Alqahtani |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: Diagnostic evaluation with the aid of biomarkers has reached newer heights to assess disease activity. Salivary calcium, magnesium, and pH are one of the biochemical parameters which can be helpful in assessing the progression of periodontal disease. Smokers are at topnotch threat for having oral diseases, predominantly periodontal diseases. The aim of this study was to assess the salivary calcium, magnesium, and pH levels in smokers compared with non-smokers with chronic periodontitis. <i>Materials and Methods</i>: The current study was conducted on 210 individuals affected with generalized chronic periodontitis, with the age group between 25 and 55 years. Based on their smoking habit, an equal number of patients were categorized into two groups; namely, group I consisted of non-smokers and group II consisted of smokers. The clinical parameters that were measured included Plaque Index (PI), Gingival Index (GI), Probing Pocket Depth (PPD), and Clinical Attachment Loss (CAL). The biochemical variables that were evaluated in the current study included salivary calcium, magnesium, and pH using an AVL9180 electrolyte analyzer (Roche, Germany). The gathered data were analyzed with an unpaired t test was using SPSS 20.0. <i>Results</i>: A statistically significant higher PPD (<i>p</i> < 0.01), CAL (<i>p</i> < 0.05), and salivary calcium levels (<i>p</i> < 0.001) were observed in the smokers’ compared with their non-smoking counterparts. Among the biochemical parameters, calcium showed a significantly (<i>p</i> < 0.001) higher level in smokers (5.79 ± 1.76) in contrast to non-smokers (3.87 ± 1.03). Additionally, a significant negative correlation (<i>p</i> < 0.05) between calcium and PPD was observed in non-smokers, whereas a non-significant inverse relation (<i>p</i> > 0.05) was seen in smokers. <i>Conclusions</i>: The present study indicates that the salivary calcium level can be a potential biochemical parameter to assess the progression of periodontal disease in smokers and non-smokers. Within the limitations of the current study, the salivary biomarkers appear to have an essential role in the identification and indication of the status of periodontal diseases. |
| first_indexed | 2024-03-11T04:46:12Z |
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| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-11T04:46:12Z |
| publishDate | 2023-04-01 |
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| series | Medicina |
| spelling | doaj.art-f66f8382c8a843d99094dffa0750ddaf2023-11-17T20:21:45ZengMDPI AGMedicina1010-660X1648-91442023-04-0159476510.3390/medicina59040765Assessment and Correlation of Salivary Ca, Mg, and pH in Smokers and Non-Smokers with Generalized Chronic PeriodontitisSaad Mohammad Alqahtani0Shankar T. Gokhale1Mohamed Fadul A. Elagib2Deepti Shrivastava3Raghavendra Reddy Nagate4Badar Awadh Mohammad Alshmrani5Abduaziz Mohammed Abdullah Alburade6Fares Mufreh Abdullah Alqahtani7Anil Kumar Nagarajappa8Valentino Natoli9Kumar Chandan Srivastava10Department of Periodontics and Community Sciences (PCS), College of Dentistry, King Khalid University, Abha 62529, Saudi ArabiaDepartment of Periodontics and Community Sciences (PCS), College of Dentistry, King Khalid University, Abha 62529, Saudi ArabiaDepartment of Periodontics and Community Sciences (PCS), College of Dentistry, King Khalid University, Abha 62529, Saudi ArabiaDepartment of Preventive dentistry, College of Dentistry, Jouf University, Sakaka 72345, Saudi ArabiaDepartment of Periodontics and Community Sciences (PCS), College of Dentistry, King Khalid University, Abha 62529, Saudi ArabiaDepartment of Periodontics and Community Sciences (PCS), College of Dentistry, King Khalid University, Abha 62529, Saudi ArabiaDepartment of Periodontics and Community Sciences (PCS), College of Dentistry, King Khalid University, Abha 62529, Saudi ArabiaDepartment of Periodontics and Community Sciences (PCS), College of Dentistry, King Khalid University, Abha 62529, Saudi ArabiaDepartment of Oral Maxillofacial Surgery & Diagnostic Sciences, College of Dentistry, Jouf University, Sakaka 72345, Saudi ArabiaDepartment of Dentistry, School of Biomedical and Health Sciences, European University of Madrid, 28670 Madrid, SpainDepartment of Oral Maxillofacial Surgery & Diagnostic Sciences, College of Dentistry, Jouf University, Sakaka 72345, Saudi Arabia<i>Background and Objectives</i>: Diagnostic evaluation with the aid of biomarkers has reached newer heights to assess disease activity. Salivary calcium, magnesium, and pH are one of the biochemical parameters which can be helpful in assessing the progression of periodontal disease. Smokers are at topnotch threat for having oral diseases, predominantly periodontal diseases. The aim of this study was to assess the salivary calcium, magnesium, and pH levels in smokers compared with non-smokers with chronic periodontitis. <i>Materials and Methods</i>: The current study was conducted on 210 individuals affected with generalized chronic periodontitis, with the age group between 25 and 55 years. Based on their smoking habit, an equal number of patients were categorized into two groups; namely, group I consisted of non-smokers and group II consisted of smokers. The clinical parameters that were measured included Plaque Index (PI), Gingival Index (GI), Probing Pocket Depth (PPD), and Clinical Attachment Loss (CAL). The biochemical variables that were evaluated in the current study included salivary calcium, magnesium, and pH using an AVL9180 electrolyte analyzer (Roche, Germany). The gathered data were analyzed with an unpaired t test was using SPSS 20.0. <i>Results</i>: A statistically significant higher PPD (<i>p</i> < 0.01), CAL (<i>p</i> < 0.05), and salivary calcium levels (<i>p</i> < 0.001) were observed in the smokers’ compared with their non-smoking counterparts. Among the biochemical parameters, calcium showed a significantly (<i>p</i> < 0.001) higher level in smokers (5.79 ± 1.76) in contrast to non-smokers (3.87 ± 1.03). Additionally, a significant negative correlation (<i>p</i> < 0.05) between calcium and PPD was observed in non-smokers, whereas a non-significant inverse relation (<i>p</i> > 0.05) was seen in smokers. <i>Conclusions</i>: The present study indicates that the salivary calcium level can be a potential biochemical parameter to assess the progression of periodontal disease in smokers and non-smokers. Within the limitations of the current study, the salivary biomarkers appear to have an essential role in the identification and indication of the status of periodontal diseases.https://www.mdpi.com/1648-9144/59/4/765periodontologyperiodontitissmokerssalivary calciumprobing pocket depthsalivary biomarkers |
| spellingShingle | Saad Mohammad Alqahtani Shankar T. Gokhale Mohamed Fadul A. Elagib Deepti Shrivastava Raghavendra Reddy Nagate Badar Awadh Mohammad Alshmrani Abduaziz Mohammed Abdullah Alburade Fares Mufreh Abdullah Alqahtani Anil Kumar Nagarajappa Valentino Natoli Kumar Chandan Srivastava Assessment and Correlation of Salivary Ca, Mg, and pH in Smokers and Non-Smokers with Generalized Chronic Periodontitis Medicina periodontology periodontitis smokers salivary calcium probing pocket depth salivary biomarkers |
| title | Assessment and Correlation of Salivary Ca, Mg, and pH in Smokers and Non-Smokers with Generalized Chronic Periodontitis |
| title_full | Assessment and Correlation of Salivary Ca, Mg, and pH in Smokers and Non-Smokers with Generalized Chronic Periodontitis |
| title_fullStr | Assessment and Correlation of Salivary Ca, Mg, and pH in Smokers and Non-Smokers with Generalized Chronic Periodontitis |
| title_full_unstemmed | Assessment and Correlation of Salivary Ca, Mg, and pH in Smokers and Non-Smokers with Generalized Chronic Periodontitis |
| title_short | Assessment and Correlation of Salivary Ca, Mg, and pH in Smokers and Non-Smokers with Generalized Chronic Periodontitis |
| title_sort | assessment and correlation of salivary ca mg and ph in smokers and non smokers with generalized chronic periodontitis |
| topic | periodontology periodontitis smokers salivary calcium probing pocket depth salivary biomarkers |
| url | https://www.mdpi.com/1648-9144/59/4/765 |
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