Connective tissue dysplasia-associated cardiac pathology in women and their newborns
Connective tissue dysplasia is the constitutional basis for cardiac pathology in women and their newborn infants. A higher serum free hydroxyproline concentration and a lower free to peptide-bound hydroxyproline ratio in women with congenital heart disease in the presence of connective tissue dyspla...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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Ltd. “The National Academy of Pediatric Science and Innovation”
2016-03-01
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| Series: | Rossijskij Vestnik Perinatologii i Pediatrii |
| Subjects: | |
| Online Access: | https://www.ped-perinatology.ru/jour/article/view/76 |
| _version_ | 1797875348279394304 |
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| author | R. R. Kildiyarova D. F. Uglova |
| author_facet | R. R. Kildiyarova D. F. Uglova |
| author_sort | R. R. Kildiyarova |
| collection | DOAJ |
| description | Connective tissue dysplasia is the constitutional basis for cardiac pathology in women and their newborn infants. A higher serum free hydroxyproline concentration and a lower free to peptide-bound hydroxyproline ratio in women with congenital heart disease in the presence of connective tissue dysplasia and a similar trend of changes in these markers in their newborns diagnosed with congenital atrial septal defect indicate the slowed metabolism of collagen and its reduced biological recycling rate, which serves as a poor prognostic sign. The mentioned biochemical markers may be used as additional criteria for preclinical diagnosis of fetal and neonatal cardiac diseases, for assessment of their prognosis and for implementation of preventive measures. |
| first_indexed | 2024-04-10T01:46:13Z |
| format | Article |
| id | doaj.art-f6702b5637d14b889e872c889d0c8717 |
| institution | Directory Open Access Journal |
| issn | 1027-4065 2500-2228 |
| language | Russian |
| last_indexed | 2024-04-10T01:46:13Z |
| publishDate | 2016-03-01 |
| publisher | Ltd. “The National Academy of Pediatric Science and Innovation” |
| record_format | Article |
| series | Rossijskij Vestnik Perinatologii i Pediatrii |
| spelling | doaj.art-f6702b5637d14b889e872c889d0c87172023-03-13T09:12:39ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282016-03-01602545669Connective tissue dysplasia-associated cardiac pathology in women and their newbornsR. R. Kildiyarova0D. F. Uglova1ГБО ВПО «Ижевская государственная медицинская академия»Республиканский клинико-диагностический центр, ИжевскConnective tissue dysplasia is the constitutional basis for cardiac pathology in women and their newborn infants. A higher serum free hydroxyproline concentration and a lower free to peptide-bound hydroxyproline ratio in women with congenital heart disease in the presence of connective tissue dysplasia and a similar trend of changes in these markers in their newborns diagnosed with congenital atrial septal defect indicate the slowed metabolism of collagen and its reduced biological recycling rate, which serves as a poor prognostic sign. The mentioned biochemical markers may be used as additional criteria for preclinical diagnosis of fetal and neonatal cardiac diseases, for assessment of their prognosis and for implementation of preventive measures.https://www.ped-perinatology.ru/jour/article/view/76новорожденные детибеременные женщиныдисплазия соединительной тканипороки сердцаобмен коллагенагидроксипролин |
| spellingShingle | R. R. Kildiyarova D. F. Uglova Connective tissue dysplasia-associated cardiac pathology in women and their newborns Rossijskij Vestnik Perinatologii i Pediatrii новорожденные дети беременные женщины дисплазия соединительной ткани пороки сердца обмен коллагена гидроксипролин |
| title | Connective tissue dysplasia-associated cardiac pathology in women and their newborns |
| title_full | Connective tissue dysplasia-associated cardiac pathology in women and their newborns |
| title_fullStr | Connective tissue dysplasia-associated cardiac pathology in women and their newborns |
| title_full_unstemmed | Connective tissue dysplasia-associated cardiac pathology in women and their newborns |
| title_short | Connective tissue dysplasia-associated cardiac pathology in women and their newborns |
| title_sort | connective tissue dysplasia associated cardiac pathology in women and their newborns |
| topic | новорожденные дети беременные женщины дисплазия соединительной ткани пороки сердца обмен коллагена гидроксипролин |
| url | https://www.ped-perinatology.ru/jour/article/view/76 |
| work_keys_str_mv | AT rrkildiyarova connectivetissuedysplasiaassociatedcardiacpathologyinwomenandtheirnewborns AT dfuglova connectivetissuedysplasiaassociatedcardiacpathologyinwomenandtheirnewborns |