Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case Report
Mounting evidence indicates that new arrhythmic events frequently occur during and after coronavirus disease (COVID-19), posing additional mortality risk in older-aged and critically ill patients. However, the underlying mechanisms and cardio pathological substrates of COVID-related arrhythmias have...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Tropical Medicine and Infectious Disease |
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| Online Access: | https://www.mdpi.com/2414-6366/7/3/43 |
| _version_ | 1797441321897558016 |
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| author | Hrvoje Jakovac Antun Ferenčić Christophe Stemberger Bojana Mohar Vitezić Dražen Cuculić |
| author_facet | Hrvoje Jakovac Antun Ferenčić Christophe Stemberger Bojana Mohar Vitezić Dražen Cuculić |
| author_sort | Hrvoje Jakovac |
| collection | DOAJ |
| description | Mounting evidence indicates that new arrhythmic events frequently occur during and after coronavirus disease (COVID-19), posing additional mortality risk in older-aged and critically ill patients. However, the underlying mechanisms and cardio pathological substrates of COVID-related arrhythmias have not been clarified yet. Here, we report findings of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigens and genes in the atrioventricular node (AV-node) of a cardiac conduction system, pointing to its direct infection as a possible arrhythmogenic factor. |
| first_indexed | 2024-03-09T12:22:21Z |
| format | Article |
| id | doaj.art-f670a79385c04227949c0f43539e7d39 |
| institution | Directory Open Access Journal |
| issn | 2414-6366 |
| language | English |
| last_indexed | 2024-03-09T12:22:21Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Tropical Medicine and Infectious Disease |
| spelling | doaj.art-f670a79385c04227949c0f43539e7d392023-11-30T22:40:11ZengMDPI AGTropical Medicine and Infectious Disease2414-63662022-03-01734310.3390/tropicalmed7030043Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case ReportHrvoje Jakovac0Antun Ferenčić1Christophe Stemberger2Bojana Mohar Vitezić3Dražen Cuculić4Department of Physiology, Immunology and Pathophysiology, Faculty of Medicine, University of Rijeka, 51000 Rijeka, CroatiaDepartment of Forensic Medicine and Criminalistics, Faculty of Medicine, University of Rijeka, 51000 Rijeka, CroatiaDepartment of Pathology, Clinical Hospital Centre Rijeka, 51000 Rijeka, CroatiaDepartment of Microbiology and Parasitology, Faculty of Medicine, University of Rijeka, 51000 Rijeka, CroatiaDepartment of Forensic Medicine and Criminalistics, Faculty of Medicine, University of Rijeka, 51000 Rijeka, CroatiaMounting evidence indicates that new arrhythmic events frequently occur during and after coronavirus disease (COVID-19), posing additional mortality risk in older-aged and critically ill patients. However, the underlying mechanisms and cardio pathological substrates of COVID-related arrhythmias have not been clarified yet. Here, we report findings of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigens and genes in the atrioventricular node (AV-node) of a cardiac conduction system, pointing to its direct infection as a possible arrhythmogenic factor.https://www.mdpi.com/2414-6366/7/3/43COVID-19SARS-CoV-2spike proteinnucleocapsid proteinAV-nodecardiac conduction system |
| spellingShingle | Hrvoje Jakovac Antun Ferenčić Christophe Stemberger Bojana Mohar Vitezić Dražen Cuculić Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case Report Tropical Medicine and Infectious Disease COVID-19 SARS-CoV-2 spike protein nucleocapsid protein AV-node cardiac conduction system |
| title | Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case Report |
| title_full | Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case Report |
| title_fullStr | Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case Report |
| title_full_unstemmed | Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case Report |
| title_short | Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case Report |
| title_sort | detection of sars cov 2 antigens in the av node of a cardiac conduction system a case report |
| topic | COVID-19 SARS-CoV-2 spike protein nucleocapsid protein AV-node cardiac conduction system |
| url | https://www.mdpi.com/2414-6366/7/3/43 |
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