miR-126 promotes M1 to M2 macrophage phenotype switching via VEGFA and KLF4

Background Macrophage polarization and microRNA play crucial roles in the development of atherosclerosis (AS). The M1 macrophage phenotype contributes to the formation of plaques, while the M2 macrophage phenotype resolves inflammation and promotes tissue repair. MiR-126 has been found to play a rol...

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Bibliographic Details
Main Authors: Xinyang Shou, Yimin Wang, Qingyu Jiang, Jun Chen, Qiang Liu
Format: Article
Language:English
Published: PeerJ Inc. 2023-03-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/15180.pdf

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