Frailty and mortality among dialysis patients

Abstract Frailty is a clinical state in which there is an increase in the individual’s vulnerability to developing increased dependency and/or mortality when exposed to a stressor. Since the mean age of dialysis patients is increasing worldwide, frailty has recently come to be considered one of the...

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Main Authors: Kosaku Nitta, Norio Hanafusa, Ken Tsuchiya
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Renal Replacement Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41100-017-0122-y
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author Kosaku Nitta
Norio Hanafusa
Ken Tsuchiya
author_facet Kosaku Nitta
Norio Hanafusa
Ken Tsuchiya
author_sort Kosaku Nitta
collection DOAJ
description Abstract Frailty is a clinical state in which there is an increase in the individual’s vulnerability to developing increased dependency and/or mortality when exposed to a stressor. Since the mean age of dialysis patients is increasing worldwide, frailty has recently come to be considered one of the risk factors for mortality in the older dialysis population. The prevalence of frailty among dialysis patients has ranged from 3.0- to 10-fold higher than that among community-dwelling elderly, depending on the method of assessing frailty and patient characteristics. Since frailty has been found to be associated with higher mortality, independent of clinical characteristics and comorbidity, interventions to improve frailty have the potential to contribute to better quality of life and lower mortality among dialysis patients. In addition, greater attention should be focused on the possibility that early rehabilitation of dialysis patients might improve poor outcomes. Clinical research should aim to devise an adequate strategy to address frailty, including identifying the optimal timing for intervention.
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spelling doaj.art-f675ff0e2eab437b9210e716bcf7d31c2022-12-22T01:19:24ZengBMCRenal Replacement Therapy2059-13812017-10-01311610.1186/s41100-017-0122-yFrailty and mortality among dialysis patientsKosaku Nitta0Norio Hanafusa1Ken Tsuchiya2Department of Medicine, Kidney Center, Tokyo Women’s Medical UniversityDepartment of Blood Purification, Kidney Center, Tokyo Women’s Medical UniversityDepartment of Blood Purification, Kidney Center, Tokyo Women’s Medical UniversityAbstract Frailty is a clinical state in which there is an increase in the individual’s vulnerability to developing increased dependency and/or mortality when exposed to a stressor. Since the mean age of dialysis patients is increasing worldwide, frailty has recently come to be considered one of the risk factors for mortality in the older dialysis population. The prevalence of frailty among dialysis patients has ranged from 3.0- to 10-fold higher than that among community-dwelling elderly, depending on the method of assessing frailty and patient characteristics. Since frailty has been found to be associated with higher mortality, independent of clinical characteristics and comorbidity, interventions to improve frailty have the potential to contribute to better quality of life and lower mortality among dialysis patients. In addition, greater attention should be focused on the possibility that early rehabilitation of dialysis patients might improve poor outcomes. Clinical research should aim to devise an adequate strategy to address frailty, including identifying the optimal timing for intervention.http://link.springer.com/article/10.1186/s41100-017-0122-yFrailtyChronic kidney diseaseDialysisMortalityIntervention
spellingShingle Kosaku Nitta
Norio Hanafusa
Ken Tsuchiya
Frailty and mortality among dialysis patients
Renal Replacement Therapy
Frailty
Chronic kidney disease
Dialysis
Mortality
Intervention
title Frailty and mortality among dialysis patients
title_full Frailty and mortality among dialysis patients
title_fullStr Frailty and mortality among dialysis patients
title_full_unstemmed Frailty and mortality among dialysis patients
title_short Frailty and mortality among dialysis patients
title_sort frailty and mortality among dialysis patients
topic Frailty
Chronic kidney disease
Dialysis
Mortality
Intervention
url http://link.springer.com/article/10.1186/s41100-017-0122-y
work_keys_str_mv AT kosakunitta frailtyandmortalityamongdialysispatients
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