Effects of chronic high fat diet on mediobasal hypothalamic satiety neuron function in POMC-Cre mice

Effects of chronic high fat diet on mediobasal hypothalamic satiety neuron function in POMC-Cre mice

Objective: The prevalence of obesity has increased over the past three decades. Proopiomelanocortin (POMC) neurons in the hypothalamic arcuate nucleus (ARC) play a vital role in induction of satiety. Chronic consumption of high-fat diet is known to reduce hypothalamic neuronal sensitivity to hormone...

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Bibliographic Details
Main Authors: Özge Başer, Yavuz Yavuz, Deniz Öykü Özen, Hüseyin Buğra Özgün, Sami Ağuş, Cihan Civan Civaş, Deniz Atasoy, Bayram Yılmaz
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Molecular Metabolism
Subjects:
Obesity
POMC neurons
Electrophysiology
Chemogenetic
High fat diet
Behavioral
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877824000358

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