An update of Nrf2 activators and inhibitors in cancer prevention/promotion

An update of Nrf2 activators and inhibitors in cancer prevention/promotion

Plain english summary The Nrf2 pathway signifies one of the most significant cell defense procedures against exogenous or endogenous stressors. Certainly, by increasing the expression of several cytoprotective genes, the transcription factor Nrf2 can shelter cells and tissues from multiple sources o...

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Bibliographic Details
Main Authors: Farhad Pouremamali, Amir Pouremamali, Mehdi Dadashpour, Narges Soozangar, Farhad Jeddi
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Cell Communication and Signaling
Subjects:
Nrf2 activators
Cancer
Nrf2 inhibitors
Keap1
Online Access:https://doi.org/10.1186/s12964-022-00906-3

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