CD271⁺ subpopulation of pancreatic stellate cells correlates with prognosis of pancreatic cancer and is regulated by interaction with cancer cells.

CD271⁺ subpopulation of pancreatic stellate cells correlates with prognosis of pancreatic cancer and is regulated by interaction with cancer cells.

Pancreatic stellate cells (PSCs) play a crucial role in the aggressive behavior of pancreatic cancer. Although heterogeneity of PSCs has been identified, the functional differences remain unclear. We characterized CD271⁺ PSCs in human pancreatic cancer. Immunohistochemistry for CD271 was performed f...

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Bibliographic Details
Main Authors: Kenji Fujiwara, Kenoki Ohuchida, Kazuhiro Mizumoto, Koji Shindo, Daiki Eguchi, Shingo Kozono, Naoki Ikenaga, Takao Ohtsuka, Shunichi Takahata, Shinichi Aishima, Masao Tanaka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3531333?pdf=render

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