Hyperthermia and cisplatin combination therapy promotes caspase-8 accumulation and activation to enhance apoptosis and pyroptosis in cancer cells

Hyperthermia and cisplatin combination therapy promotes caspase-8 accumulation and activation to enhance apoptosis and pyroptosis in cancer cells

AbstractBackground Hyperthermia can play a synergistic role with chemotherapy in combination therapy. Although the association between caspase activation, apoptosis, and pyroptosis have been published for both cisplatin (CDDP) and hyperthermia therapies independently, the interactions between these...

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Bibliographic Details
Main Authors: Guanghui Zi, Jin Chen, Yatu Peng, Yue Wang, Baowei Peng
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:International Journal of Hyperthermia
Subjects:
Hyperthermia
Caspase-8
p62
Ubiquitination
Pyroptosis
Cisplatin
Online Access:https://www.tandfonline.com/doi/10.1080/02656736.2024.2325489

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