The DA antagonist tiapride impairs context-related extinction learning in a novel context without affecting renewal

The DA antagonist tiapride impairs context-related extinction learning in a novel context without affecting renewal

Renewal describes the recovery of an extinguished response if recall is tested in a context different from the extinction context. Behavioral studies demonstrated that attention to relevant context strengthens renewal. Neurotransmitters mediating attention and learning such as the dopaminergic (DA)...

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Bibliographic Details
Main Authors: Silke eLissek, Benjamin eGlaubitz, Oliver T Wolf, Martin eTegenthoff
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Dopamine
Hippocampus
fMRI
prefrontal cortex (PFC)
renewal effect
Tiapride
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00238/full

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