Multimodal treatment with curative intent in a germline BRCA2 mutant metastatic ampullary adenocarcinoma: a case report

Multimodal treatment with curative intent in a germline BRCA2 mutant metastatic ampullary adenocarcinoma: a case report

Abstract Background Cancers of the Vater ampulla (ampullary cancers, ACs) account for less than 1% of all gastrointestinal tumors. ACs are usually diagnosed at advanced stage, with poor prognosis and limited therapeutic options. BRCA2 mutations are identified in up to 14% of ACs and, differently fro...

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Main Authors: Gianluca Mauri, Viviana Gori, Giorgio Patelli, Laura Roazzi, Francesco Rizzetto, Luciano De Carlis, Anna Mariani, Ugo Cavallari, Elisabetta Prada, Tiziana Cipani, Maria Costanza Aquilano, Emanuela Bonoldi, Angelo Vanzulli, Salvatore Siena, Andrea Sartore-Bianchi
Format: Article
Language:English
Published: BMC 2023-03-01
Series:World Journal of Surgical Oncology
Subjects:
Case report
Surgical metastasectomy
BRCA
Ampullary cancer
Platinum toxicity and sensitivity
Online Access:https://doi.org/10.1186/s12957-023-02976-0

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