Polylactic Acid-Based Patterned Matrixes for Site-Specific Delivery of Neuropeptides On-Demand: Functional NGF Effects on Human Neuronal Cells

Polylactic Acid-Based Patterned Matrixes for Site-Specific Delivery of Neuropeptides On-Demand: Functional NGF Effects on Human Neuronal Cells

The patterned microchamber arrays based on biocompatible polymers are a versatile cargo delivery system for drug storage and site-/time-specific drug release on demand. However, functional evidence of their action on nerve cells, in particular their potential for enabling patterned neuronal morphoge...

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Bibliographic Details
Main Authors: Olga A. Sindeeva, Olga Kopach, Maxim A. Kurochkin, Andrei Sapelkin, David J. Gould, Dmitri A. Rusakov, Gleb B. Sukhorukov
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
polylactic acid (PLA)
patterned microchamber array
drug delivery system
NGF
human N2A cells
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00497/full

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