Factor H Is Bound by Outer Membrane-Displayed Carbohydrate Metabolism Enzymes of Extraintestinal Pathogenic Escherichia coli and Contributes to Opsonophagocytosis Resistance in Bacteria
Extraintestinal pathogenic Escherichia coli (ExPEC) causes bloodstream infections in humans and animals. Complement escape is a prerequisite for bacteria to survive in the bloodstream. Factor H (FH) is an important regulatory protein of the complement system. In this study, ExPEC was found to bind F...
Main Authors: | Yu Sun, Bin Xu, Xiangkai Zhuge, Fang Tang, Xuhang Wang, Qianwen Gong, Rui Chen, Feng Xue, Jianjun Dai |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-01-01
|
Series: | Frontiers in Cellular and Infection Microbiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcimb.2020.592906/full |
Similar Items
-
Extraintestinal pathogenic Escherichia coli utilizes the surface-expressed elongation factor Tu to bind and acquire iron from holo-transferrin
by: Yu Sun, et al.
Published: (2022-12-01) -
Extraintestinal Pathogenic Escherichia coli Utilizes Surface-Located Elongation Factor G to Acquire Iron from Holo-Transferrin
by: Yu Sun, et al.
Published: (2022-04-01) -
Development of flow cytometric opsonophagocytosis and antibody-mediated complement deposition assays for non-typeable Haemophilus influenzae
by: Stephen R. Thomas, et al.
Published: (2018-10-01) -
Alternative Complement Pathway Inhibition Abrogates Pneumococcal Opsonophagocytosis in Vaccine-Naïve, but Not in Vaccinated Individuals
by: Lukas Muri, et al.
Published: (2021-10-01) -
Acetate metabolic requirement of avian pathogenic Escherichia coli promotes its intracellular proliferation within macrophage
by: Xiangkai Zhuge, et al.
Published: (2019-05-01)