Effects of legacy and emerging per- and polyfluoroalkyl substances on PPARα/β/γ regulation and osteogenic/adipogenic differentiation

Effects of legacy and emerging per- and polyfluoroalkyl substances on PPARα/β/γ regulation and osteogenic/adipogenic differentiation

As the primary molecular target, there is still a gap between the peroxisome proliferator-activated receptors (PPARs) regulation and the adverse health effects caused by per- and polyfluoroalkyl substances (PFASs). The effects of PFASs on cellular differentiation regulated by PPARs is likely signifi...

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Bibliographic Details
Main Authors: Hui Qin, Yuxin Niu, Haiyang Luan, Minghan Li, Lu Zheng, Yifan Pan, Wei Liu
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Environment International
Subjects:
Perfluorinated substances
PPARs
Human mesenchymal stem cells
Multipotent differentiation
Molecular initiating event
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412022005116

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