Viral RNA and infectious virus in mucosal specimens from guinea pigs modelling early phases of lethal and non-lethal Lassa fever

Viral RNA and infectious virus in mucosal specimens from guinea pigs modelling early phases of lethal and non-lethal Lassa fever

Lassa fever (LF) is endemic to broad regions of West Africa. Infection with Lassa virus (LASV), the etiologic agent of LF, results in a spectrum of clinical signs in humans, including severe and lethal hemorrhagic disease. Person-to-person transmission occurs through direct contact with body fluids...

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Bibliographic Details
Main Authors: Stephen R. Welch, Sarah C. Genzer, JoAnn D. Coleman-McCray, Jessica R. Harmon, Florine E.M. Scholte, Joel M. Montgomery, Christina F. Spiropoulou, Jessica R. Spengler
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Emerging Microbes and Infections
Subjects:
Lassa virus
arenavirus
viral hemorrhagic fever
virus isolation
body fluids
mucosal swab
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2022.2071637

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