Nano-Neurogenesis for CNS Diseases and Disorders

Neurogenesis encompasses the formation and development of neurons in the mammalian brain, mainly occurring in hippocampus and the olfactory system. This process is rapid, accurate, and very sensitive to the external stressors including environment, diet, age, anxiety, stress, depression, diet, and h...

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Main Authors: Sneham Tiwari, Ajeet Kaushik
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Nanotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnano.2022.931259/full
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author Sneham Tiwari
Sneham Tiwari
Ajeet Kaushik
author_facet Sneham Tiwari
Sneham Tiwari
Ajeet Kaushik
author_sort Sneham Tiwari
collection DOAJ
description Neurogenesis encompasses the formation and development of neurons in the mammalian brain, mainly occurring in hippocampus and the olfactory system. This process is rapid, accurate, and very sensitive to the external stressors including environment, diet, age, anxiety, stress, depression, diet, and hormones. The range of stressors is big and directly impacts the generation, maturation and migration, efficacy, and myelination of the neuronal cells. The field of regenerative medicine focuses on combating the direct or indirect effects of these stressors on the process of neurogenesis, and ensures increased general and neuronal communications and functioning. Understanding the deep secrets of brain signaling and devising ways to increase drug availability is tough, considering the complexity and intricate details of the neuronal networks and signaling in the CNS. It is imperative to understand this complexity and introduce potent and efficacious ways to combat diseases. This perspective offers an insight into how neurogenesis could be aided by nanotechnology and what plausible nanomaterials are available to culminate neurogenesis-related neurological disorders. The nanomaterials are promising as they are minute, robust, and effective and help in diagnostics and therapeutics such as drug delivery, maturation and neuroprotection, neurogenesis, imaging, and neurosurgery.
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spelling doaj.art-f68abc1358ff4841bcf022bb11260d7e2022-12-22T03:03:42ZengFrontiers Media S.A.Frontiers in Nanotechnology2673-30132022-07-01410.3389/fnano.2022.931259931259Nano-Neurogenesis for CNS Diseases and DisordersSneham Tiwari0Sneham Tiwari1Ajeet Kaushik2Division of Genetics and Genomics, Boston Children’s Hospital, Boston, MA, United StatesDepartment of Immunology and Nano-Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, United StatesNanoBioTech Laboratory, Department of Environmental Engineering, Florida Polytechnic University, Lakeland, FL, United StatesNeurogenesis encompasses the formation and development of neurons in the mammalian brain, mainly occurring in hippocampus and the olfactory system. This process is rapid, accurate, and very sensitive to the external stressors including environment, diet, age, anxiety, stress, depression, diet, and hormones. The range of stressors is big and directly impacts the generation, maturation and migration, efficacy, and myelination of the neuronal cells. The field of regenerative medicine focuses on combating the direct or indirect effects of these stressors on the process of neurogenesis, and ensures increased general and neuronal communications and functioning. Understanding the deep secrets of brain signaling and devising ways to increase drug availability is tough, considering the complexity and intricate details of the neuronal networks and signaling in the CNS. It is imperative to understand this complexity and introduce potent and efficacious ways to combat diseases. This perspective offers an insight into how neurogenesis could be aided by nanotechnology and what plausible nanomaterials are available to culminate neurogenesis-related neurological disorders. The nanomaterials are promising as they are minute, robust, and effective and help in diagnostics and therapeutics such as drug delivery, maturation and neuroprotection, neurogenesis, imaging, and neurosurgery.https://www.frontiersin.org/articles/10.3389/fnano.2022.931259/fullneurogenesisbrain diseasesdementiananomedicinenanobiotechnology
spellingShingle Sneham Tiwari
Sneham Tiwari
Ajeet Kaushik
Nano-Neurogenesis for CNS Diseases and Disorders
Frontiers in Nanotechnology
neurogenesis
brain diseases
dementia
nanomedicine
nanobiotechnology
title Nano-Neurogenesis for CNS Diseases and Disorders
title_full Nano-Neurogenesis for CNS Diseases and Disorders
title_fullStr Nano-Neurogenesis for CNS Diseases and Disorders
title_full_unstemmed Nano-Neurogenesis for CNS Diseases and Disorders
title_short Nano-Neurogenesis for CNS Diseases and Disorders
title_sort nano neurogenesis for cns diseases and disorders
topic neurogenesis
brain diseases
dementia
nanomedicine
nanobiotechnology
url https://www.frontiersin.org/articles/10.3389/fnano.2022.931259/full
work_keys_str_mv AT snehamtiwari nanoneurogenesisforcnsdiseasesanddisorders
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