Nano-Neurogenesis for CNS Diseases and Disorders
Neurogenesis encompasses the formation and development of neurons in the mammalian brain, mainly occurring in hippocampus and the olfactory system. This process is rapid, accurate, and very sensitive to the external stressors including environment, diet, age, anxiety, stress, depression, diet, and h...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2022-07-01
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Series: | Frontiers in Nanotechnology |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fnano.2022.931259/full |
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author | Sneham Tiwari Sneham Tiwari Ajeet Kaushik |
author_facet | Sneham Tiwari Sneham Tiwari Ajeet Kaushik |
author_sort | Sneham Tiwari |
collection | DOAJ |
description | Neurogenesis encompasses the formation and development of neurons in the mammalian brain, mainly occurring in hippocampus and the olfactory system. This process is rapid, accurate, and very sensitive to the external stressors including environment, diet, age, anxiety, stress, depression, diet, and hormones. The range of stressors is big and directly impacts the generation, maturation and migration, efficacy, and myelination of the neuronal cells. The field of regenerative medicine focuses on combating the direct or indirect effects of these stressors on the process of neurogenesis, and ensures increased general and neuronal communications and functioning. Understanding the deep secrets of brain signaling and devising ways to increase drug availability is tough, considering the complexity and intricate details of the neuronal networks and signaling in the CNS. It is imperative to understand this complexity and introduce potent and efficacious ways to combat diseases. This perspective offers an insight into how neurogenesis could be aided by nanotechnology and what plausible nanomaterials are available to culminate neurogenesis-related neurological disorders. The nanomaterials are promising as they are minute, robust, and effective and help in diagnostics and therapeutics such as drug delivery, maturation and neuroprotection, neurogenesis, imaging, and neurosurgery. |
first_indexed | 2024-04-13T03:53:56Z |
format | Article |
id | doaj.art-f68abc1358ff4841bcf022bb11260d7e |
institution | Directory Open Access Journal |
issn | 2673-3013 |
language | English |
last_indexed | 2024-04-13T03:53:56Z |
publishDate | 2022-07-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Nanotechnology |
spelling | doaj.art-f68abc1358ff4841bcf022bb11260d7e2022-12-22T03:03:42ZengFrontiers Media S.A.Frontiers in Nanotechnology2673-30132022-07-01410.3389/fnano.2022.931259931259Nano-Neurogenesis for CNS Diseases and DisordersSneham Tiwari0Sneham Tiwari1Ajeet Kaushik2Division of Genetics and Genomics, Boston Children’s Hospital, Boston, MA, United StatesDepartment of Immunology and Nano-Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, United StatesNanoBioTech Laboratory, Department of Environmental Engineering, Florida Polytechnic University, Lakeland, FL, United StatesNeurogenesis encompasses the formation and development of neurons in the mammalian brain, mainly occurring in hippocampus and the olfactory system. This process is rapid, accurate, and very sensitive to the external stressors including environment, diet, age, anxiety, stress, depression, diet, and hormones. The range of stressors is big and directly impacts the generation, maturation and migration, efficacy, and myelination of the neuronal cells. The field of regenerative medicine focuses on combating the direct or indirect effects of these stressors on the process of neurogenesis, and ensures increased general and neuronal communications and functioning. Understanding the deep secrets of brain signaling and devising ways to increase drug availability is tough, considering the complexity and intricate details of the neuronal networks and signaling in the CNS. It is imperative to understand this complexity and introduce potent and efficacious ways to combat diseases. This perspective offers an insight into how neurogenesis could be aided by nanotechnology and what plausible nanomaterials are available to culminate neurogenesis-related neurological disorders. The nanomaterials are promising as they are minute, robust, and effective and help in diagnostics and therapeutics such as drug delivery, maturation and neuroprotection, neurogenesis, imaging, and neurosurgery.https://www.frontiersin.org/articles/10.3389/fnano.2022.931259/fullneurogenesisbrain diseasesdementiananomedicinenanobiotechnology |
spellingShingle | Sneham Tiwari Sneham Tiwari Ajeet Kaushik Nano-Neurogenesis for CNS Diseases and Disorders Frontiers in Nanotechnology neurogenesis brain diseases dementia nanomedicine nanobiotechnology |
title | Nano-Neurogenesis for CNS Diseases and Disorders |
title_full | Nano-Neurogenesis for CNS Diseases and Disorders |
title_fullStr | Nano-Neurogenesis for CNS Diseases and Disorders |
title_full_unstemmed | Nano-Neurogenesis for CNS Diseases and Disorders |
title_short | Nano-Neurogenesis for CNS Diseases and Disorders |
title_sort | nano neurogenesis for cns diseases and disorders |
topic | neurogenesis brain diseases dementia nanomedicine nanobiotechnology |
url | https://www.frontiersin.org/articles/10.3389/fnano.2022.931259/full |
work_keys_str_mv | AT snehamtiwari nanoneurogenesisforcnsdiseasesanddisorders AT snehamtiwari nanoneurogenesisforcnsdiseasesanddisorders AT ajeetkaushik nanoneurogenesisforcnsdiseasesanddisorders |