Novel Delivery of Mitoxantrone with Hydrophobically Modified Pullulan Nanoparticles to Inhibit Bladder Cancer Cell and the Effect of Nano-drug Size on Inhibition Efficiency

Novel Delivery of Mitoxantrone with Hydrophobically Modified Pullulan Nanoparticles to Inhibit Bladder Cancer Cell and the Effect of Nano-drug Size on Inhibition Efficiency

Abstract Reducing the dosage of chemotherapeutic drugs via enhancing the delivery efficiency using novel nanoparticles has great potential for cancer treatment. Here, we focused on improving mitoxantrone delivery by using cholesterol-substituted pullulan polymers (CHPs) and selected a suitable nano-...

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Bibliographic Details
Main Authors: Xiaojun Tao, Ting Tao, Yi Wen, Jiajin Yi, Lihua He, Zixuan Huang, Yu Nie, Xiaoyan Yao, Yingying Wang, Chunlian He, Xiaoping Yang
Format: Article
Language:English
Published: SpringerOpen 2018-10-01
Series:Nanoscale Research Letters
Subjects:
Hydrophobic
Cholesterol-substituted pullulan
Nanoparticle
Size
Bladder cancer
Online Access:http://link.springer.com/article/10.1186/s11671-018-2769-x

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