Targeting EGFR/HER2 pathways enhances the antiproliferative effect of gemcitabine in biliary tract and gallbladder carcinomas

Targeting EGFR/HER2 pathways enhances the antiproliferative effect of gemcitabine in biliary tract and gallbladder carcinomas

<p>Abstract</p> <p>Background</p> <p>Advanced biliary tract carcinomas (BTCs) have poor prognosis and limited therapeutic options. Therefore, it is crucial to combine standard therapies with molecular targeting. In this study EGFR, HER2, and their molecular transducers...

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Main Authors: Bardelli Alberto, Risio Mauro, Chiorino Giovanna, Casorzo Laura, Migliardi Giorgia, Cavalloni Giuliana, Penachioni Junia Y, Peraldo-Neia Caterina, Sarotto Ivana, Pignochino Ymera, Aglietta Massimo, Leone Francesco
Format: Article
Language:English
Published: BMC 2010-11-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/631

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http://www.biomedcentral.com/1471-2407/10/631

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