Mycobacterium tuberculosis inhibits METTL14-mediated m6A methylation of Nox2 mRNA and suppresses anti-TB immunity

Mycobacterium tuberculosis inhibits METTL14-mediated m6A methylation of Nox2 mRNA and suppresses anti-TB immunity

Abstract Internal N6-methyladenosine (m6A) modifications are among the most abundant modifications of messenger RNA, playing a critical role in diverse biological and pathological processes. However, the functional role and regulatory mechanism of m6A modifications in the immune response to Mycobact...

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Bibliographic Details
Main Authors: Mingtong Ma, Yongjia Duan, Cheng Peng, You Wu, Xinning Zhang, Boran Chang, Fei Wang, Hua Yang, Ruijuan Zheng, Hongyu Cheng, Yuanna Cheng, Yifan He, Jingping Huang, Jinming Lei, Hanyu Ma, Liru Li, Jie Wang, Xiaochen Huang, Fen Tang, Jun Liu, Jinsong Li, Ruoyan Ying, Peng Wang, Wei Sha, Yawei Gao, Lin Wang, Baoxue Ge
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-024-00653-4

Internet

https://doi.org/10.1038/s41421-024-00653-4

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