Poly (Lactic Acid) Nanoparticles: A Promising Hope to Overcome the Cancers
Nanoparticles are used mainly for the transmission of the therapeutic molecules (like drugs, proteins, or DNA) to the organ/tissue of human body. Polymeric nanoparticles are mostly applied for therapeutic effectiveness in cancer therapy. The micro environment of tumor tissues in vessels can assist n...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Fasa University of Medical Sciences
2021-05-01
|
| Series: | Journal of Advanced Biomedical Sciences |
| Subjects: | |
| Online Access: | http://jabs.fums.ac.ir/article-1-2379-en.pdf |
| _version_ | 1797679597194575872 |
|---|---|
| author | Farnaz Fattahi Tahereh Zamani |
| author_facet | Farnaz Fattahi Tahereh Zamani |
| author_sort | Farnaz Fattahi |
| collection | DOAJ |
| description | Nanoparticles are used mainly for the transmission of the therapeutic molecules (like drugs, proteins, or DNA) to the organ/tissue of human body. Polymeric nanoparticles are mostly applied for therapeutic effectiveness in cancer therapy. The micro environment of tumor tissues in vessels can assist nanoparticles in achieving their anticipated accumulation. Poly (lactic acid)(PLA) is a novel green polymer with natural sources (like sweet potato and sugar cane). PLA is a linear aliphatic which has great sustainability, renewability and compostability. PLA has popper mechanical, thermal and barrier properties. This biomaterial is thermoplastic polyester with biocompatibility, non-toxicity and biodegradability. Various forms of PLA nanoparticles are synthetized for biomedical applications like cancer treatments and wound healing process. This review article introduces the various structures of polylactic acid nanoparticles used to deliver anticancer drugs. Furthermore, the investigational approaches that are considered for using PLA nanoparticles in treatment of different types of cancers will be reported briefly. |
| first_indexed | 2024-03-11T23:17:06Z |
| format | Article |
| id | doaj.art-f691fcbdfa9043859267285c2793cf0a |
| institution | Directory Open Access Journal |
| issn | 2228-5105 2783-1523 |
| language | English |
| last_indexed | 2024-03-11T23:17:06Z |
| publishDate | 2021-05-01 |
| publisher | Fasa University of Medical Sciences |
| record_format | Article |
| series | Journal of Advanced Biomedical Sciences |
| spelling | doaj.art-f691fcbdfa9043859267285c2793cf0a2023-09-20T21:28:33ZengFasa University of Medical SciencesJournal of Advanced Biomedical Sciences2228-51052783-15232021-05-0111237913814Poly (Lactic Acid) Nanoparticles: A Promising Hope to Overcome the CancersFarnaz Fattahi0Tahereh Zamani1 Department of Textile Engineering, Isfahan University of Technology, Isfahan, Iran The Genetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Nanoparticles are used mainly for the transmission of the therapeutic molecules (like drugs, proteins, or DNA) to the organ/tissue of human body. Polymeric nanoparticles are mostly applied for therapeutic effectiveness in cancer therapy. The micro environment of tumor tissues in vessels can assist nanoparticles in achieving their anticipated accumulation. Poly (lactic acid)(PLA) is a novel green polymer with natural sources (like sweet potato and sugar cane). PLA is a linear aliphatic which has great sustainability, renewability and compostability. PLA has popper mechanical, thermal and barrier properties. This biomaterial is thermoplastic polyester with biocompatibility, non-toxicity and biodegradability. Various forms of PLA nanoparticles are synthetized for biomedical applications like cancer treatments and wound healing process. This review article introduces the various structures of polylactic acid nanoparticles used to deliver anticancer drugs. Furthermore, the investigational approaches that are considered for using PLA nanoparticles in treatment of different types of cancers will be reported briefly.http://jabs.fums.ac.ir/article-1-2379-en.pdfpoly (lactic acid)polymeric nanoparticlecancer treatmentdrug delivergene deliverytumor cell |
| spellingShingle | Farnaz Fattahi Tahereh Zamani Poly (Lactic Acid) Nanoparticles: A Promising Hope to Overcome the Cancers Journal of Advanced Biomedical Sciences poly (lactic acid) polymeric nanoparticle cancer treatment drug deliver gene delivery tumor cell |
| title | Poly (Lactic Acid) Nanoparticles: A Promising Hope to Overcome the Cancers |
| title_full | Poly (Lactic Acid) Nanoparticles: A Promising Hope to Overcome the Cancers |
| title_fullStr | Poly (Lactic Acid) Nanoparticles: A Promising Hope to Overcome the Cancers |
| title_full_unstemmed | Poly (Lactic Acid) Nanoparticles: A Promising Hope to Overcome the Cancers |
| title_short | Poly (Lactic Acid) Nanoparticles: A Promising Hope to Overcome the Cancers |
| title_sort | poly lactic acid nanoparticles a promising hope to overcome the cancers |
| topic | poly (lactic acid) polymeric nanoparticle cancer treatment drug deliver gene delivery tumor cell |
| url | http://jabs.fums.ac.ir/article-1-2379-en.pdf |
| work_keys_str_mv | AT farnazfattahi polylacticacidnanoparticlesapromisinghopetoovercomethecancers AT taherehzamani polylacticacidnanoparticlesapromisinghopetoovercomethecancers |