Caryopathic effect of extract Fasciola hepatica on laboratory mice
Effect of extract of trematodes Fasciola hepatica on body cells of laboratory mice is studied. A single intraperitoneal injection of rectified extract of fascioles was made into non-linear white male mice at the dose of 100 mg/kg of extract en- zyme. The total number of leucocytes, lymphocytes, mono...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Federal Scientific Centre VIEV
2016-05-01
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| Series: | Российский паразитологический журнал |
| Subjects: | |
| Online Access: | https://vniigis.elpub.ru/jour/article/view/213 |
| Summary: | Effect of extract of trematodes Fasciola hepatica on body cells of laboratory mice is studied. A single intraperitoneal injection of rectified extract of fascioles was made into non-linear white male mice at the dose of 100 mg/kg of extract en- zyme. The total number of leucocytes, lymphocytes, monocytes and granulocytes has been registered. Blood films as well as red bone marrow- and seminal vesicles smears were stained using a Romanowsky - type stain and microscoped. Mitotic index was determined and number of abnormal mitotic figures calculated. It is found that a single intraperitoneal injection of rectified extract F. hepatica into non-linear white male mice increases the number of aneuploid cells of red bone marrow as well as stimulates production of lymphocytes and eosinophils. The re- ceived results confirm the ability of helminths to cause the host cell mitotic distur- bances |
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| ISSN: | 1998-8435 2541-7843 |