Remodeling of dermal adipose tissue alleviates cutaneous toxicity induced by anti-EGFR therapy

Remodeling of dermal adipose tissue alleviates cutaneous toxicity induced by anti-EGFR therapy

Anti-epidermal growth factor receptor (EGFR) therapy–associated cutaneous toxicity is a syndrome characterized by papulopustular rash, local inflammation, folliculitis, and microbial infection, resulting in a decrease in quality of life and dose interruption. However, no effective clinical intervent...

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Bibliographic Details
Main Authors: Leying Chen, Qing You, Min Liu, Shuaihu Li, Zhaoyu Wu, Jiajun Hu, Yurui Ma, Liangyong Xia, Ying Zhou, Nan Xu, Shiyi Zhang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-03-01
Series:eLife
Subjects:
dermal adipose tissue
anti-EGFR therapy
cutaneous toxicity
PPARγ
Online Access:https://elifesciences.org/articles/72443

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