Blood metagenomics next-generation sequencing has advantages in detecting difficult-to-cultivate pathogens, and mixed infections: results from a real-world cohort

Blood metagenomics next-generation sequencing has advantages in detecting difficult-to-cultivate pathogens, and mixed infections: results from a real-world cohort

BackgroundBlood is a common sample source for metagenomics next-generation sequencing (mNGS) in clinical practice. In this study, we aimed to detect the diagnostic value of blood mNGS in a large real-world cohorts.MethodsBlood mNGS results of 1,046 cases were collected and analyzed along with other...

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Bibliographic Details
Main Authors: Mengjia Qian, Chang Li, Miaomiao Zhang, Yanxia Zhan, Bijun Zhu, Lingyan Wang, Qi Shen, Lei Yue, Hao Chen, Yunfeng Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
metagenomics next-generation sequencing (mNGS)
diagnosis
infection
blood
real-world
large cohort
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1268281/full

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