Increased Nociceptive Responses in Streptozotocin-Induced Diabetic Rats and the Related Expression of Spinal NR2B Subunit of -Methyl-D-Aspartate Receptors

Increased Nociceptive Responses in Streptozotocin-Induced Diabetic Rats and the Related Expression of Spinal NR2B Subunit of -Methyl-D-Aspartate Receptors

BackgroundThis study investigated the role of NR2B in a modulated pain process in the painful diabetic neuropathy (PDN) rat using various pain stimuli.MethodsThirty-two Sprague-Dawley male rats were randomly allocated into four groups (n=8): control, diabetes mellitus (DM) rats and diabetic rats tre...

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Bibliographic Details
Main Authors: Che Aishah Nazariah Ismail, Rapeah Suppian, Che Badariah Abd Aziz, Khalilah Haris, Idris Long
Format: Article
Language:English
Published: Korean Diabetes Association 2019-04-01
Series:Diabetes & Metabolism Journal
Subjects:
diabetic neuropathies
hyperalgesia
ifenprodil
nr2b nmda receptor
pain measurement
Online Access:http://e-dmj.org/upload/pdf/dmj-43-222.pdf

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