Genistein protects against hyperglycemia and fatty liver disease in diet-induced prediabetes mice via activating hepatic insulin signaling pathway

Genistein protects against hyperglycemia and fatty liver disease in diet-induced prediabetes mice via activating hepatic insulin signaling pathway

IntroductionInsulin signaling via the insulin receptor (IR) may be associated with the amelioration of diet-induced metabolic syndrome. Genistein, a soy isoflavone, has been suggested to play a role in the amelioration of high-fat diet-induced metabolic disorders.MethodsHere, we aimed to explore whe...

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Bibliographic Details
Main Authors: Nana Zhang, Weiyue Zhang, Xinxin Guo, Jianlin Liu, Shuying Li, Hongtai Zhang, Bei Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Nutrition
Subjects:
genistein
high-fat diet
hyperglycemia
insulin resistance
fatty liver
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.1072044/full

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