PPFIA1 expression associates with poor response to endocrine treatment in luminal breast cancer

PPFIA1 expression associates with poor response to endocrine treatment in luminal breast cancer

Abstract Background PPFIA1 is an important regulator of cell migration and invasion, regulating focal adhesion signalling and disassembly. PPFIA1 is frequently amplified in breast cancer, and recent functional studies indicate that PPFIA1 is an important promoter of migration and invasion in breast...

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Bibliographic Details
Main Authors: Lutfi H. Alfarsi, Rokaya El Ansari, Madeleine L. Craze, Brendah K. Masisi, Ian O. Ellis, Emad A. Rakha, Andrew R. Green
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Cancer
Subjects:
Breast cancer
Oestrogen receptor
Endocrine resistance
PPFIA1
Liprin
Predictive biomarker
Online Access:http://link.springer.com/article/10.1186/s12885-020-06939-6

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