Structural Basis of Targeting the Exportin CRM1 in Cancer

Recent studies have demonstrated the interference of nucleocytoplasmic trafficking with the establishment and maintenance of various cancers. Nucleocytoplasmic transport is highly regulated and coordinated, involving different nuclear transport factors or receptors, importins and exportins, that med...

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Autori principali: Achim Dickmanns, Thomas Monecke, Ralf Ficner
Natura: Articolo
Lingua:English
Pubblicazione: MDPI AG 2015-09-01
Serie:Cells
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Accesso online:http://www.mdpi.com/2073-4409/4/3/538