Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Abstract Specific protein–protein interactions are central to all processes that underlie cell physiology. Numerous studies have together identified hundreds of thousands of human protein–protein interactions. However, many interactions remain to be discovered, and low affinity, conditional, and cel...

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Bibliographic Details
Main Authors: Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Format: Article
Language:English
Published: Springer Nature 2022-01-01
Series:Molecular Systems Biology
Subjects:
intrinsically disordered regions
peptides
phage display
protein–protein interactions
short linear motifs
Online Access:https://doi.org/10.15252/msb.202110584

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