The outcomes of revision surgery for a failed ankle arthroplasty: a systematic review and meta-analysis

Aims: Revision rates for ankle arthroplasties are higher than hip or knee arthroplasties. When a total ankle arthroplasty (TAA) fails, it can either undergo revision to another ankle replacement, revision of the TAA to ankle arthrodesis (fusion), or amputation. Currently there is a paucity of liter...

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Main Authors: Toby Jennison, Claire Spolton-Dean, Hannah Rottenburg, Obioha Ukoumunne, Ian Sharpe, Andrew Goldberg
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2022-07-01
Series:Bone & Joint Open
Subjects:
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2633-1462.37.BJO-2022-0038.R1
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author Toby Jennison
Claire Spolton-Dean
Hannah Rottenburg
Obioha Ukoumunne
Ian Sharpe
Andrew Goldberg
author_facet Toby Jennison
Claire Spolton-Dean
Hannah Rottenburg
Obioha Ukoumunne
Ian Sharpe
Andrew Goldberg
author_sort Toby Jennison
collection DOAJ
description Aims: Revision rates for ankle arthroplasties are higher than hip or knee arthroplasties. When a total ankle arthroplasty (TAA) fails, it can either undergo revision to another ankle replacement, revision of the TAA to ankle arthrodesis (fusion), or amputation. Currently there is a paucity of literature on the outcomes of these revisions. The aim of this meta-analysis is to assess the outcomes of revision TAA with respect to surgery type, functional outcomes, and reoperations. Methods: A systematic review was conducted using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Medline, Embase, Cinahl, and Cochrane reviews were searched for relevant papers. Papers analyzing surgical treatment for failed ankle arthroplasties were included. All papers were reviewed by two authors. Overall, 34 papers met the inclusion criteria. A meta-analysis of proportions was performed. Results: Six papers analyzed all-cause reoperations of revision ankle arthroplasties, and 14 papers analyzed failures of conversion of a TAA to fusion. It was found that 26.9% (95% confidence interval (CI) 15.4% to 40.1%) of revision ankle arthroplasties required further surgical intervention and 13.0% (95% CI 4.9% to 23.4%) of conversion to fusions; 14.4% (95% CI 8.4% to 21.4%) of revision ankle arthroplasties failed and 8% (95% CI 4% to 13%) of conversion to fusions failed. Conclusion: Revision of primary TAA can be an effective procedure with improved functional outcomes, but has considerable risks of failure and reoperation, especially in those with periprosthetic joint infection. In those who undergo conversion of TAA to fusion, there are high rates of nonunion. Further comparative studies are required to compare both operative techniques. Cite this article: Bone Jt Open 2022;3(7):596–606.
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spelling doaj.art-f6ae5d34b1754b069a216741bdaee93a2022-12-22T01:55:48ZengThe British Editorial Society of Bone & Joint SurgeryBone & Joint Open2633-14622022-07-013759660610.1302/2633-1462.37.BJO-2022-0038.R1The outcomes of revision surgery for a failed ankle arthroplasty: a systematic review and meta-analysisToby Jennison0Claire Spolton-Dean1Hannah Rottenburg2Obioha Ukoumunne3Ian Sharpe4Andrew Goldberg5Royal Devon and Exeter NHS Foundation Trust, Exeter, UKRoyal Devon and Exeter NHS Foundation Trust, Exeter, UKUniversity of Exeter, Exeter, UKUniversity of Exeter, Exeter, UKRoyal Devon and Exeter NHS Foundation Trust, Exeter, UKWellington Hospital, London, UKAims: Revision rates for ankle arthroplasties are higher than hip or knee arthroplasties. When a total ankle arthroplasty (TAA) fails, it can either undergo revision to another ankle replacement, revision of the TAA to ankle arthrodesis (fusion), or amputation. Currently there is a paucity of literature on the outcomes of these revisions. The aim of this meta-analysis is to assess the outcomes of revision TAA with respect to surgery type, functional outcomes, and reoperations. Methods: A systematic review was conducted using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Medline, Embase, Cinahl, and Cochrane reviews were searched for relevant papers. Papers analyzing surgical treatment for failed ankle arthroplasties were included. All papers were reviewed by two authors. Overall, 34 papers met the inclusion criteria. A meta-analysis of proportions was performed. Results: Six papers analyzed all-cause reoperations of revision ankle arthroplasties, and 14 papers analyzed failures of conversion of a TAA to fusion. It was found that 26.9% (95% confidence interval (CI) 15.4% to 40.1%) of revision ankle arthroplasties required further surgical intervention and 13.0% (95% CI 4.9% to 23.4%) of conversion to fusions; 14.4% (95% CI 8.4% to 21.4%) of revision ankle arthroplasties failed and 8% (95% CI 4% to 13%) of conversion to fusions failed. Conclusion: Revision of primary TAA can be an effective procedure with improved functional outcomes, but has considerable risks of failure and reoperation, especially in those with periprosthetic joint infection. In those who undergo conversion of TAA to fusion, there are high rates of nonunion. Further comparative studies are required to compare both operative techniques. Cite this article: Bone Jt Open 2022;3(7):596–606.https://online.boneandjoint.org.uk/doi/epdf/10.1302/2633-1462.37.BJO-2022-0038.R1ankle replacementrevision ankle replacementankle arthrodesisankle arthroplastiesrevision surgeryrevision total ankle arthroplastytotal ankle arthroplasty (taa)periprosthetic joint infectionnonunionamputationsfunctional outcomesprimary total ankle arthroplastysurgical treatment
spellingShingle Toby Jennison
Claire Spolton-Dean
Hannah Rottenburg
Obioha Ukoumunne
Ian Sharpe
Andrew Goldberg
The outcomes of revision surgery for a failed ankle arthroplasty: a systematic review and meta-analysis
Bone & Joint Open
ankle replacement
revision ankle replacement
ankle arthrodesis
ankle arthroplasties
revision surgery
revision total ankle arthroplasty
total ankle arthroplasty (taa)
periprosthetic joint infection
nonunion
amputations
functional outcomes
primary total ankle arthroplasty
surgical treatment
title The outcomes of revision surgery for a failed ankle arthroplasty: a systematic review and meta-analysis
title_full The outcomes of revision surgery for a failed ankle arthroplasty: a systematic review and meta-analysis
title_fullStr The outcomes of revision surgery for a failed ankle arthroplasty: a systematic review and meta-analysis
title_full_unstemmed The outcomes of revision surgery for a failed ankle arthroplasty: a systematic review and meta-analysis
title_short The outcomes of revision surgery for a failed ankle arthroplasty: a systematic review and meta-analysis
title_sort outcomes of revision surgery for a failed ankle arthroplasty a systematic review and meta analysis
topic ankle replacement
revision ankle replacement
ankle arthrodesis
ankle arthroplasties
revision surgery
revision total ankle arthroplasty
total ankle arthroplasty (taa)
periprosthetic joint infection
nonunion
amputations
functional outcomes
primary total ankle arthroplasty
surgical treatment
url https://online.boneandjoint.org.uk/doi/epdf/10.1302/2633-1462.37.BJO-2022-0038.R1
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