Are hypothalamic- pituitary (HP) axis deficiencies after whole brain radiotherapy (WBRT) of relevance for adult cancer patients? – a systematic review of the literature

Are hypothalamic- pituitary (HP) axis deficiencies after whole brain radiotherapy (WBRT) of relevance for adult cancer patients? – a systematic review of the literature

Abstract Background Cranial radiotherapy (cRT) can induce hormonal deficiencies as a consequence of significant doses to the hypothalamic-pituitary (HP) axis. In contrast to profound endocrinological follow-up data from survivors of childhood cancer treated with cRT, little knowledge exists for adul...

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Bibliographic Details
Main Authors: P. Mehta, F. B. Fahlbusch, D. Rades, S. M. Schmid, J. Gebauer, S. Janssen
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Cancer
Subjects:
Whole brain radiotherapy
Endocrine deficiencies
Hypothalamus
Pituitary
Hypopituitarism
Online Access:https://doi.org/10.1186/s12885-019-6431-5

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