Hallmarks of Splicing Defects in Cancer: Clinical Applications in the Era of Personalized Medicine

Hallmarks of Splicing Defects in Cancer: Clinical Applications in the Era of Personalized Medicine

Alternative splicing promotes proteome diversity by using limited number of genes, a key control point of gene expression. Splicing is carried out by large macromolecular machineries, called spliceosome, composed of small RNAs and proteins. Alternative splicing is regulated by splicing regulatory &l...

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Bibliographic Details
Main Authors: Mohammad Alinoor Rahman, Farhana Nasrin, Sonali Bhattacharjee, Saikat Nandi
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
splicing
spliceosome
cancer therapies
oncogenesis
RNA processing
Online Access:https://www.mdpi.com/2072-6694/12/6/1381

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