Limb Laterality Discrimination, Evoked Sensations and Somatosensory Behavior in Fibromyalgia Syndrome: A Cross-Sectional Study
The main objective of this study was to assess the status of body schema using limb laterality discrimination tasks and pain measurement variables of patients with FMS compared to healthy subjects. The secondary aim was to analyze the relationships between laterality discrimination with respect to s...
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MDPI AG
2022-07-01
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| Online Access: | https://www.mdpi.com/2076-3417/12/15/7495 |
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| author | Víctor Riquelme-Aguado Antonio Gil-Crujera Josué Fernández-Carnero Ferran Cuenca-Martínez Francisco Gómez Esquer |
| author_facet | Víctor Riquelme-Aguado Antonio Gil-Crujera Josué Fernández-Carnero Ferran Cuenca-Martínez Francisco Gómez Esquer |
| author_sort | Víctor Riquelme-Aguado |
| collection | DOAJ |
| description | The main objective of this study was to assess the status of body schema using limb laterality discrimination tasks and pain measurement variables of patients with FMS compared to healthy subjects. The secondary aim was to analyze the relationships between laterality discrimination with respect to somatosensory variables. Thirty female patients with FMS (with a mean age of 52.43 ± 11.82 years) and thirty healthy women (with a mean age of 47.93 ± 5.92 years) were recruited. The main outcome measures were laterality discrimination, referral of evoked sensations, pressure pain threshold and conditioned pain modulation. The main analysis showed that patients with FMS have a longer reaction time for laterality discrimination in hands (hands—20 images, t = 4.044, <i>p</i> < 0.0001, <i>d</i> = 1.04; hands—50 images t = 4.012, <i>p</i> < 0.0001, <i>d</i> = 1.31; feet—20 images t = 2.982, <i>p</i> < 0.01, <i>d</i> = 0.76; feet—50 images, t = 2.159, <i>p</i> < 0.05, <i>d</i> = 0.55). With regard the secondary analysis, patients with FM have higher mechanical hyperalgesia (t = −9.550; <i>p</i> < 0.0001, d = 2.51) and decreased response to conditioned pain modulation compared with healthy subjects (t = 15.519; <i>p</i> < 0.0001, d = 4.17). A positive correlation was found in patients with FMS between greater laterality discrimination ability and better function of conditioned pain modulation (hands r = 0.676, <i>p</i> < 0.0001; feet r = 0.485, <i>p</i> < 0.01). In conclusion, patients with FMS have a longer reaction time and lower accuracy for laterality discrimination, increased mechanical hyperalgesia and decreased conditioned pain modulation compared to healthy subjects. Finally, it seems that there is a positive correlation between greater laterality discrimination ability and better conditioned pain modulation function. |
| first_indexed | 2024-03-09T05:38:33Z |
| format | Article |
| id | doaj.art-f6b2296a048b4559801bdaeaaff9a9c5 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-09T05:38:33Z |
| publishDate | 2022-07-01 |
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| series | Applied Sciences |
| spelling | doaj.art-f6b2296a048b4559801bdaeaaff9a9c52023-12-03T12:27:37ZengMDPI AGApplied Sciences2076-34172022-07-011215749510.3390/app12157495Limb Laterality Discrimination, Evoked Sensations and Somatosensory Behavior in Fibromyalgia Syndrome: A Cross-Sectional StudyVíctor Riquelme-Aguado0Antonio Gil-Crujera1Josué Fernández-Carnero2Ferran Cuenca-Martínez3Francisco Gómez Esquer4Escuela Internacional de Doctorado, Department of Basic Health Sciences, Universidad Rey Juan Carlos, 28922 Alcorcón, SpainDepartment of Basic Health Sciences, Rey Juan Carlos University, 28922 Madrid, SpainGrupo Multidisciplinar de Investigación y Tratamiento del Dolor, Grupo de Excelencia Investigadora URJC-Banco de Santander, 28922 Madrid, SpainIntervention for Health Research Group (EXINH-RG), Department of Physiotherapy, University of Valencia, 46010 Valencia, SpainDepartment of Basic Health Sciences, Rey Juan Carlos University, 28922 Madrid, SpainThe main objective of this study was to assess the status of body schema using limb laterality discrimination tasks and pain measurement variables of patients with FMS compared to healthy subjects. The secondary aim was to analyze the relationships between laterality discrimination with respect to somatosensory variables. Thirty female patients with FMS (with a mean age of 52.43 ± 11.82 years) and thirty healthy women (with a mean age of 47.93 ± 5.92 years) were recruited. The main outcome measures were laterality discrimination, referral of evoked sensations, pressure pain threshold and conditioned pain modulation. The main analysis showed that patients with FMS have a longer reaction time for laterality discrimination in hands (hands—20 images, t = 4.044, <i>p</i> < 0.0001, <i>d</i> = 1.04; hands—50 images t = 4.012, <i>p</i> < 0.0001, <i>d</i> = 1.31; feet—20 images t = 2.982, <i>p</i> < 0.01, <i>d</i> = 0.76; feet—50 images, t = 2.159, <i>p</i> < 0.05, <i>d</i> = 0.55). With regard the secondary analysis, patients with FM have higher mechanical hyperalgesia (t = −9.550; <i>p</i> < 0.0001, d = 2.51) and decreased response to conditioned pain modulation compared with healthy subjects (t = 15.519; <i>p</i> < 0.0001, d = 4.17). A positive correlation was found in patients with FMS between greater laterality discrimination ability and better function of conditioned pain modulation (hands r = 0.676, <i>p</i> < 0.0001; feet r = 0.485, <i>p</i> < 0.01). In conclusion, patients with FMS have a longer reaction time and lower accuracy for laterality discrimination, increased mechanical hyperalgesia and decreased conditioned pain modulation compared to healthy subjects. Finally, it seems that there is a positive correlation between greater laterality discrimination ability and better conditioned pain modulation function.https://www.mdpi.com/2076-3417/12/15/7495fibromyalgialimb laterality recognitionconditioned pain modulationmechanical hyperalgesia |
| spellingShingle | Víctor Riquelme-Aguado Antonio Gil-Crujera Josué Fernández-Carnero Ferran Cuenca-Martínez Francisco Gómez Esquer Limb Laterality Discrimination, Evoked Sensations and Somatosensory Behavior in Fibromyalgia Syndrome: A Cross-Sectional Study Applied Sciences fibromyalgia limb laterality recognition conditioned pain modulation mechanical hyperalgesia |
| title | Limb Laterality Discrimination, Evoked Sensations and Somatosensory Behavior in Fibromyalgia Syndrome: A Cross-Sectional Study |
| title_full | Limb Laterality Discrimination, Evoked Sensations and Somatosensory Behavior in Fibromyalgia Syndrome: A Cross-Sectional Study |
| title_fullStr | Limb Laterality Discrimination, Evoked Sensations and Somatosensory Behavior in Fibromyalgia Syndrome: A Cross-Sectional Study |
| title_full_unstemmed | Limb Laterality Discrimination, Evoked Sensations and Somatosensory Behavior in Fibromyalgia Syndrome: A Cross-Sectional Study |
| title_short | Limb Laterality Discrimination, Evoked Sensations and Somatosensory Behavior in Fibromyalgia Syndrome: A Cross-Sectional Study |
| title_sort | limb laterality discrimination evoked sensations and somatosensory behavior in fibromyalgia syndrome a cross sectional study |
| topic | fibromyalgia limb laterality recognition conditioned pain modulation mechanical hyperalgesia |
| url | https://www.mdpi.com/2076-3417/12/15/7495 |
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