Can Erectile Dysfunction in Young Patients Serve as a Surrogate Marker for Coronary Artery Disease?
Introduction: Early diagnosis and expeditious management of coronary artery disease (CAD) has a rewarding survival benefit. Aim: To study whether erectile dysfunction (ED) serves as a surrogate marker for CAD in a young patient. Settings and Design: Males (n=207) between ages 20-60 years with E...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2015-11-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/6709/14207_CE(RA1)_F(T)_PF1(BMAK)_PFA(AK)_PF2(PAG).pdf |
| _version_ | 1819121644288868352 |
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| author | Kaje Yogesh Dattatrya Tanwar Harshawardhan Vedpalsingh Wagaska Vinayak Gorakhnath Patwardhan Sujata Kiran |
| author_facet | Kaje Yogesh Dattatrya Tanwar Harshawardhan Vedpalsingh Wagaska Vinayak Gorakhnath Patwardhan Sujata Kiran |
| author_sort | Kaje Yogesh Dattatrya |
| collection | DOAJ |
| description | Introduction: Early diagnosis and expeditious management of
coronary artery disease (CAD) has a rewarding survival benefit.
Aim: To study whether erectile dysfunction (ED) serves as a
surrogate marker for CAD in a young patient.
Settings and Design: Males (n=207) between ages 20-60 years
with ED were evaluated prospectively for risk factors for CAD.
Materials and Methods: Blood Glucose Levels (BGL) fasting
and post meal), lipid profile (LP) and 12 lead electrocardiogram
(ECG) was done in all of them. International Index of Erectile
Function-5 (IEF-5) was used for the evaluation of ED. Those
with abnormal parameters were assessed by cardiologists
by echocardiography, stress test and if necessary coronary
angiography (Non-Invasive or Invasive).
Statistical Analysis: All the data were analysed using SPSS.
16 statistical software (SPSS Inc., Chicago, IL, USA). All data
are expressed as mean and standard deviation. The Student’s
t-test was used to compare means between groups, and the
chi-square test was used to compare proportions between the
groups. P-value <0.05 was considered statistically significant. All
confidence intervals (CIs) are two tailed and calculated at the 0.05
level.
Results: Out of 207, 149 patients had at least one abnormal
screening parameter. All underwent cardiology consultation and
2D ECHO and Stress test. Thirty six patients underwent coronary
angiography. CAD was found in 22 patients. Of these, 19 patients
had severe ED. Nine patients were between 20-40 years of age
(13.23%). All 9 young patients had deranged LP; severe ED. Six
patients were smokers while nobody was hypertensive.
Conclusion: ED serves as a surrogate marker for CAD in young
patients (p=0.001). Presence of risk factors and lab abnormalities
in young patients with ED warrants a cardiology referral to detect
CAD. |
| first_indexed | 2024-12-22T06:39:50Z |
| format | Article |
| id | doaj.art-f6b330ceacba4bd49efd096f59f5dce0 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-22T06:39:50Z |
| publishDate | 2015-11-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-f6b330ceacba4bd49efd096f59f5dce02022-12-21T18:35:28ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-11-01911PC01PC0310.7860/JCDR/2015/14207.6709Can Erectile Dysfunction in Young Patients Serve as a Surrogate Marker for Coronary Artery Disease?Kaje Yogesh Dattatrya0Tanwar Harshawardhan Vedpalsingh1Wagaska Vinayak Gorakhnath2Patwardhan Sujata Kiran3Registrar, Department of Urology, Seth G.S Medical College & KEM Hospital, Mumbai, Maharashtra, India.Registrar, Department of Urology, Seth G.S Medical College & KEM Hospital, Mumbai, Maharashtra, India.Registrar, Department of Urology, Seth G.S Medical College & KEM Hospital, Mumbai, Maharashtra, India.Head of Department, Department of urology, Seth G.S Medical College & KEM Hospital, Mumbai, Maharashtra, India.Introduction: Early diagnosis and expeditious management of coronary artery disease (CAD) has a rewarding survival benefit. Aim: To study whether erectile dysfunction (ED) serves as a surrogate marker for CAD in a young patient. Settings and Design: Males (n=207) between ages 20-60 years with ED were evaluated prospectively for risk factors for CAD. Materials and Methods: Blood Glucose Levels (BGL) fasting and post meal), lipid profile (LP) and 12 lead electrocardiogram (ECG) was done in all of them. International Index of Erectile Function-5 (IEF-5) was used for the evaluation of ED. Those with abnormal parameters were assessed by cardiologists by echocardiography, stress test and if necessary coronary angiography (Non-Invasive or Invasive). Statistical Analysis: All the data were analysed using SPSS. 16 statistical software (SPSS Inc., Chicago, IL, USA). All data are expressed as mean and standard deviation. The Student’s t-test was used to compare means between groups, and the chi-square test was used to compare proportions between the groups. P-value <0.05 was considered statistically significant. All confidence intervals (CIs) are two tailed and calculated at the 0.05 level. Results: Out of 207, 149 patients had at least one abnormal screening parameter. All underwent cardiology consultation and 2D ECHO and Stress test. Thirty six patients underwent coronary angiography. CAD was found in 22 patients. Of these, 19 patients had severe ED. Nine patients were between 20-40 years of age (13.23%). All 9 young patients had deranged LP; severe ED. Six patients were smokers while nobody was hypertensive. Conclusion: ED serves as a surrogate marker for CAD in young patients (p=0.001). Presence of risk factors and lab abnormalities in young patients with ED warrants a cardiology referral to detect CAD.https://jcdr.net/articles/PDF/6709/14207_CE(RA1)_F(T)_PF1(BMAK)_PFA(AK)_PF2(PAG).pdfcoronary angiographyinternational index of erectile function-5 (ief-5)smokers |
| spellingShingle | Kaje Yogesh Dattatrya Tanwar Harshawardhan Vedpalsingh Wagaska Vinayak Gorakhnath Patwardhan Sujata Kiran Can Erectile Dysfunction in Young Patients Serve as a Surrogate Marker for Coronary Artery Disease? Journal of Clinical and Diagnostic Research coronary angiography international index of erectile function-5 (ief-5) smokers |
| title | Can Erectile Dysfunction in Young Patients Serve as a Surrogate Marker for Coronary Artery Disease? |
| title_full | Can Erectile Dysfunction in Young Patients Serve as a Surrogate Marker for Coronary Artery Disease? |
| title_fullStr | Can Erectile Dysfunction in Young Patients Serve as a Surrogate Marker for Coronary Artery Disease? |
| title_full_unstemmed | Can Erectile Dysfunction in Young Patients Serve as a Surrogate Marker for Coronary Artery Disease? |
| title_short | Can Erectile Dysfunction in Young Patients Serve as a Surrogate Marker for Coronary Artery Disease? |
| title_sort | can erectile dysfunction in young patients serve as a surrogate marker for coronary artery disease |
| topic | coronary angiography international index of erectile function-5 (ief-5) smokers |
| url | https://jcdr.net/articles/PDF/6709/14207_CE(RA1)_F(T)_PF1(BMAK)_PFA(AK)_PF2(PAG).pdf |
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