The value of elastography strain rate ratio in benign and malignant BI-RADS-US 3-4 breast masses
The current study aims to investigate the value of strain rate ratio (SR) of elastography for benign and malignant breast masses categorized by Breast Imaging Reporting and Data System for Ultrasonography (BI-RADS-US) category 3-4. Ultrasonographic data of 1099 breast masses that underwent both ela...
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| Format: | Article |
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Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2023-12-01
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| Series: | Biomolecules & Biomedicine |
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| Online Access: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/9878 |
| _version_ | 1797261407160369152 |
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| author | Xinping Li Weixu Sun Hongbiao Zhang |
| author_facet | Xinping Li Weixu Sun Hongbiao Zhang |
| author_sort | Xinping Li |
| collection | DOAJ |
| description |
The current study aims to investigate the value of strain rate ratio (SR) of elastography for benign and malignant breast masses categorized by Breast Imaging Reporting and Data System for Ultrasonography (BI-RADS-US) category 3-4. Ultrasonographic data of 1099 breast masses that underwent both elastography and pathological examination were retrospectively analyzed by non-parametric test, consistency analysis and receiver operating characteristic (ROC) curve sequentially. ROC curve was used to evaluate the diagnostic effect of SR method in different BI-RADS categories of breast lesions. The maximum Youden index obtained from the ROC curve was 0.845. At a cut-off value of 3.57, the SR values’ diagnostic sensitivity, specificity, accuracy, positive predictive value and negative predictive value for distinguishing benign and malignant breast lesions were 85.7 %, 98.8 %, 93.6 %, 97.9 % and 91.45 %, respectively. Consistency analysis showed that the consistency between SR value and pathological diagnosis was 93.6 % (κ = 0.864). In addition, the SR values between benign and malignant lesions of BI-RADS 3 and 4 were statistically different (P < 0.001). ROC analysis indicated that the diagnostic area under curve (AUC) for SR value in BI-RADS 3, 4a, 4b and 4c lesions were 0.985, 0.866, 0.793 and 0.916, respectively. In addition, the study observed 58 cases of missed diagnosis and 20 cases of misdiagnosis in evaluating benign and malignant breast lesions. The elastic SR ratio method has a good diagnostic value for the evaluation of breast masses, particularly for lesions with a score of 3-4. The elastic SR ratio method is instrumental in enhancing the accuracy of diagnosis.
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| first_indexed | 2024-04-24T23:40:43Z |
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| id | doaj.art-f6b60f8fe1754b44bdcd1bb4c87c04d9 |
| institution | Directory Open Access Journal |
| issn | 2831-0896 2831-090X |
| language | English |
| last_indexed | 2024-04-24T23:40:43Z |
| publishDate | 2023-12-01 |
| publisher | Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina |
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| series | Biomolecules & Biomedicine |
| spelling | doaj.art-f6b60f8fe1754b44bdcd1bb4c87c04d92024-03-15T13:21:01ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2023-12-0110.17305/bb.2023.9878The value of elastography strain rate ratio in benign and malignant BI-RADS-US 3-4 breast massesXinping Li0Weixu Sun1Hongbiao Zhang2Department of Ultrasonography, The First People’s Hospital of Yuhang District, Hangzhou, ChinaDepartment of Ultrasonography, The First People’s Hospital of Yuhang District, Hangzhou, ChinaDepartment of Ultrasonography, The First People’s Hospital of Yuhang District, Hangzhou, China The current study aims to investigate the value of strain rate ratio (SR) of elastography for benign and malignant breast masses categorized by Breast Imaging Reporting and Data System for Ultrasonography (BI-RADS-US) category 3-4. Ultrasonographic data of 1099 breast masses that underwent both elastography and pathological examination were retrospectively analyzed by non-parametric test, consistency analysis and receiver operating characteristic (ROC) curve sequentially. ROC curve was used to evaluate the diagnostic effect of SR method in different BI-RADS categories of breast lesions. The maximum Youden index obtained from the ROC curve was 0.845. At a cut-off value of 3.57, the SR values’ diagnostic sensitivity, specificity, accuracy, positive predictive value and negative predictive value for distinguishing benign and malignant breast lesions were 85.7 %, 98.8 %, 93.6 %, 97.9 % and 91.45 %, respectively. Consistency analysis showed that the consistency between SR value and pathological diagnosis was 93.6 % (κ = 0.864). In addition, the SR values between benign and malignant lesions of BI-RADS 3 and 4 were statistically different (P < 0.001). ROC analysis indicated that the diagnostic area under curve (AUC) for SR value in BI-RADS 3, 4a, 4b and 4c lesions were 0.985, 0.866, 0.793 and 0.916, respectively. In addition, the study observed 58 cases of missed diagnosis and 20 cases of misdiagnosis in evaluating benign and malignant breast lesions. The elastic SR ratio method has a good diagnostic value for the evaluation of breast masses, particularly for lesions with a score of 3-4. The elastic SR ratio method is instrumental in enhancing the accuracy of diagnosis. https://www.bjbms.org/ojs/index.php/bjbms/article/view/9878Ultrasound elastography (UE)breast massesstrain rate ratio (SR)breast imaging reporting and data system (BI-RADS) classificationreceiver operating characteristic (ROC) curve |
| spellingShingle | Xinping Li Weixu Sun Hongbiao Zhang The value of elastography strain rate ratio in benign and malignant BI-RADS-US 3-4 breast masses Biomolecules & Biomedicine Ultrasound elastography (UE) breast masses strain rate ratio (SR) breast imaging reporting and data system (BI-RADS) classification receiver operating characteristic (ROC) curve |
| title | The value of elastography strain rate ratio in benign and malignant BI-RADS-US 3-4 breast masses |
| title_full | The value of elastography strain rate ratio in benign and malignant BI-RADS-US 3-4 breast masses |
| title_fullStr | The value of elastography strain rate ratio in benign and malignant BI-RADS-US 3-4 breast masses |
| title_full_unstemmed | The value of elastography strain rate ratio in benign and malignant BI-RADS-US 3-4 breast masses |
| title_short | The value of elastography strain rate ratio in benign and malignant BI-RADS-US 3-4 breast masses |
| title_sort | value of elastography strain rate ratio in benign and malignant bi rads us 3 4 breast masses |
| topic | Ultrasound elastography (UE) breast masses strain rate ratio (SR) breast imaging reporting and data system (BI-RADS) classification receiver operating characteristic (ROC) curve |
| url | https://www.bjbms.org/ojs/index.php/bjbms/article/view/9878 |
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