CYP2D6 allele distribution in Macedonians, Albanians and Romanies in the Republic of Macedonia

CYP2D6 allele distribution in Macedonians, Albanians and Romanies in the Republic of Macedonia

Cytochrome P450 2D6 (CYP2D6) is an enzyme of great importance for the metabolism of clinically used drugs. More than 100 variants of the CYP2D6 gene have been identified so far. The aim of this study was to investigate the allele distribution of CYP2D6 gene variants in 100 individuals of each of the...

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Bibliographic Details
Main Authors: Kuzmanovska M, Dimishkovska M, Maleva Kostovska I, Noveski P, Sukarova Stefanovska E, Plaseska-Karanfilska D
Format: Article
Language:English
Published: Sciendo 2015-12-01
Series:Balkan Journal of Medical Genetics
Subjects:
allele
cyp2d6 gene
cyp450
ethnic groups
extensive metabolizers (ems)
intermediate metabolizers (ims)
poor metabolizers (pms)
ultrarapid metabolizers (ums)
Online Access:https://doi.org/10.1515/bjmg-2015-0086

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