Phosphorylated alpha‐synuclein in Iba1‐positive macrophages in the skin of patients with Parkinson's disease

Abstract Background Increasing evidence suggests that alpha‐synuclein (αSyn) accumulation in cholinergic and adrenergic fibers in the skin is a useful biomarker to diagnose idiopathic Parkinson's disease (IPD). It has been widely reported that phosphorylated αSyn (p‐αSyn) deposits in autonomic...

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Bibliographische Detailangaben
Hauptverfasser: Hideki Oizumi, Kenshi Yamasaki, Hiroyoshi Suzuki, Saki Ohshiro, Yuko Saito, Shigeo Murayama, Yoko Sugimura, Takafumi Hasegawa, Kohji Fukunaga, Atsushi Takeda
Format: Artikel
Sprache:English
Veröffentlicht: Wiley 2022-08-01
Schriftenreihe:Annals of Clinical and Translational Neurology
Online Zugang:https://doi.org/10.1002/acn3.51610