Alginate-Chitosan Hydrogels Containing shRNA Plasmid for Inhibition of CTNNB1 Expression in Breast Cancer Cells

The hydrogels prepared with alginate and chitosan polymers were prepared to deliver the shRNA-encoding plasmid (pshRNA) to MDA-MB-231 cells for the inhibition of β-catenin (CTNNB1), which was reported to be overexpressed in breast cancer. Polyion complex hydrogels prepared using sodium alginate and...

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Bibliographic Details
Main Authors: Birnur Cömez, Suna Özbaş
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Gels
Subjects:
Online Access:https://www.mdpi.com/2310-2861/9/7/541

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