Natural Chinese herbs for the prevention and treatment of acute pancreatitis: a narrative review
Acute pancreatitis (AP) is a disease characterized by local inflammation in the pancreas, followed by trypsin activation, and may result from multiple etiologies. Approximately 20% of AP can progress to severe acute pancreatitis (SAP), which can lead to systemic inflammatory response syndrome (SIRS)...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Health/LWW
2022-12-01
|
| Series: | Journal of Pancreatology |
| Online Access: | http://journals.lww.com/10.1097/JP9.0000000000000111 |
| _version_ | 1828086644386824192 |
|---|---|
| author | Jiaqi Cui Di Wu Huimin Zhou Haiyan Chen Zhixia Dong Jun Yang |
| author_facet | Jiaqi Cui Di Wu Huimin Zhou Haiyan Chen Zhixia Dong Jun Yang |
| author_sort | Jiaqi Cui |
| collection | DOAJ |
| description | Acute pancreatitis (AP) is a disease characterized by local inflammation in the pancreas, followed by trypsin activation, and may result from multiple etiologies. Approximately 20% of AP can progress to severe acute pancreatitis (SAP), which can lead to systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndromes (MODS). SAP mortality rates have remained high in recent years, but there are currently no specific drugs designed to reduce these rates. Clinical studies have shown that patients can reduce the symptoms of the disease and slow down the development of the disease after taking the Chinese medicine decoction. Basic studies have shown that in AP or SAP disease models, the use of Chinese medicine monomers can improve the condition of rates. These natural Chinese herbal products can improve pancreatitis, given their ability to act on multiple targets. However, they have not been widely employed clinically and studied sufficiently and thoroughly. Therefore, this review aimed to summarize the pathophysiological mechanisms underlying pancreatitis and review the potential role of natural Chinese herbs (monomers and decoctions) in clinical and basic research. |
| first_indexed | 2024-04-11T04:58:14Z |
| format | Article |
| id | doaj.art-f6cdba64e4984884ab2b7321529c59ef |
| institution | Directory Open Access Journal |
| issn | 2096-5664 |
| language | English |
| last_indexed | 2024-04-11T04:58:14Z |
| publishDate | 2022-12-01 |
| publisher | Wolters Kluwer Health/LWW |
| record_format | Article |
| series | Journal of Pancreatology |
| spelling | doaj.art-f6cdba64e4984884ab2b7321529c59ef2022-12-26T06:04:53ZengWolters Kluwer Health/LWWJournal of Pancreatology2096-56642022-12-015418619710.1097/JP9.0000000000000111202212000-00007Natural Chinese herbs for the prevention and treatment of acute pancreatitis: a narrative reviewJiaqi Cui0Di Wu1Huimin Zhou2Haiyan Chen3Zhixia Dong4Jun Yang5a Department of General Surgery, Wuxi Institute of Hepatobiliary Surgery, Affiliated Hospital of Jiangnan University, Wuxi 214000, Chinaa Department of General Surgery, Wuxi Institute of Hepatobiliary Surgery, Affiliated Hospital of Jiangnan University, Wuxi 214000, Chinaa Department of General Surgery, Wuxi Institute of Hepatobiliary Surgery, Affiliated Hospital of Jiangnan University, Wuxi 214000, Chinaa Department of General Surgery, Wuxi Institute of Hepatobiliary Surgery, Affiliated Hospital of Jiangnan University, Wuxi 214000, Chinaa Department of General Surgery, Wuxi Institute of Hepatobiliary Surgery, Affiliated Hospital of Jiangnan University, Wuxi 214000, Chinaa Department of General Surgery, Wuxi Institute of Hepatobiliary Surgery, Affiliated Hospital of Jiangnan University, Wuxi 214000, ChinaAcute pancreatitis (AP) is a disease characterized by local inflammation in the pancreas, followed by trypsin activation, and may result from multiple etiologies. Approximately 20% of AP can progress to severe acute pancreatitis (SAP), which can lead to systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndromes (MODS). SAP mortality rates have remained high in recent years, but there are currently no specific drugs designed to reduce these rates. Clinical studies have shown that patients can reduce the symptoms of the disease and slow down the development of the disease after taking the Chinese medicine decoction. Basic studies have shown that in AP or SAP disease models, the use of Chinese medicine monomers can improve the condition of rates. These natural Chinese herbal products can improve pancreatitis, given their ability to act on multiple targets. However, they have not been widely employed clinically and studied sufficiently and thoroughly. Therefore, this review aimed to summarize the pathophysiological mechanisms underlying pancreatitis and review the potential role of natural Chinese herbs (monomers and decoctions) in clinical and basic research.http://journals.lww.com/10.1097/JP9.0000000000000111 |
| spellingShingle | Jiaqi Cui Di Wu Huimin Zhou Haiyan Chen Zhixia Dong Jun Yang Natural Chinese herbs for the prevention and treatment of acute pancreatitis: a narrative review Journal of Pancreatology |
| title | Natural Chinese herbs for the prevention and treatment of acute pancreatitis: a narrative review |
| title_full | Natural Chinese herbs for the prevention and treatment of acute pancreatitis: a narrative review |
| title_fullStr | Natural Chinese herbs for the prevention and treatment of acute pancreatitis: a narrative review |
| title_full_unstemmed | Natural Chinese herbs for the prevention and treatment of acute pancreatitis: a narrative review |
| title_short | Natural Chinese herbs for the prevention and treatment of acute pancreatitis: a narrative review |
| title_sort | natural chinese herbs for the prevention and treatment of acute pancreatitis a narrative review |
| url | http://journals.lww.com/10.1097/JP9.0000000000000111 |
| work_keys_str_mv | AT jiaqicui naturalchineseherbsforthepreventionandtreatmentofacutepancreatitisanarrativereview AT diwu naturalchineseherbsforthepreventionandtreatmentofacutepancreatitisanarrativereview AT huiminzhou naturalchineseherbsforthepreventionandtreatmentofacutepancreatitisanarrativereview AT haiyanchen naturalchineseherbsforthepreventionandtreatmentofacutepancreatitisanarrativereview AT zhixiadong naturalchineseherbsforthepreventionandtreatmentofacutepancreatitisanarrativereview AT junyang naturalchineseherbsforthepreventionandtreatmentofacutepancreatitisanarrativereview |