Regulator Non-coding RNAs: miRNA, siRNA, piRNA, lncRNA, circRNA

Gene expression and its regulation play a central role in maintaining life and generation in all living things. According to the central dogma of genetics, DNA plays a central role in gene expression, RNA is synthesized from DNA, and protein is synthesized from RNA. According to recent research resu...

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Main Author: Ertan Altayli
Format: Article
Language:English
Published: National Scientific Medical Center 2020-11-01
Series:Ķazaķstannyṇ Klinikalyķ Medicinasy
Subjects:
Online Access:https://www.clinmedkaz.org/download/regulator-non-coding-rnas-mirna-sirna-pirna-lncrna-circrna-9258.pdf
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author Ertan Altayli
author_facet Ertan Altayli
author_sort Ertan Altayli
collection DOAJ
description Gene expression and its regulation play a central role in maintaining life and generation in all living things. According to the central dogma of genetics, DNA plays a central role in gene expression, RNA is synthesized from DNA, and protein is synthesized from RNA. According to recent research results, human DNA produces more regulator non-coding RNA than protein coding RNAs. These RNAs act as important functional regulatory molecules in various cellular processes, including chromatin remodeling, transcription, post-transcriptional modifications and signal transfer. Therefore, the regulator ncRNAs act as key regulators of physiological programs in terms of development and disease. In this review, the main structural and functional properties of miRNA, siRNA, piRNA, lncRNA and circRNA defined as regulator ncRNAs are reviewed.
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spelling doaj.art-f6ce56ffa34b4023a0188302b547abaa2022-12-21T23:49:06ZengNational Scientific Medical CenterĶazaķstannyṇ Klinikalyķ Medicinasy1812-28922313-15192020-11-01660293910.23950/jcmk/9258Regulator Non-coding RNAs: miRNA, siRNA, piRNA, lncRNA, circRNAErtan Altayli0Department of Medical Biology, Gülhane Faculty of Medicine, Health Sciences University, Ankara, TurkeyGene expression and its regulation play a central role in maintaining life and generation in all living things. According to the central dogma of genetics, DNA plays a central role in gene expression, RNA is synthesized from DNA, and protein is synthesized from RNA. According to recent research results, human DNA produces more regulator non-coding RNA than protein coding RNAs. These RNAs act as important functional regulatory molecules in various cellular processes, including chromatin remodeling, transcription, post-transcriptional modifications and signal transfer. Therefore, the regulator ncRNAs act as key regulators of physiological programs in terms of development and disease. In this review, the main structural and functional properties of miRNA, siRNA, piRNA, lncRNA and circRNA defined as regulator ncRNAs are reviewed.https://www.clinmedkaz.org/download/regulator-non-coding-rnas-mirna-sirna-pirna-lncrna-circrna-9258.pdfmiRNAsiRNApiRNAlncRNAcircRNA
spellingShingle Ertan Altayli
Regulator Non-coding RNAs: miRNA, siRNA, piRNA, lncRNA, circRNA
Ķazaķstannyṇ Klinikalyķ Medicinasy
miRNA
siRNA
piRNA
lncRNA
circRNA
title Regulator Non-coding RNAs: miRNA, siRNA, piRNA, lncRNA, circRNA
title_full Regulator Non-coding RNAs: miRNA, siRNA, piRNA, lncRNA, circRNA
title_fullStr Regulator Non-coding RNAs: miRNA, siRNA, piRNA, lncRNA, circRNA
title_full_unstemmed Regulator Non-coding RNAs: miRNA, siRNA, piRNA, lncRNA, circRNA
title_short Regulator Non-coding RNAs: miRNA, siRNA, piRNA, lncRNA, circRNA
title_sort regulator non coding rnas mirna sirna pirna lncrna circrna
topic miRNA
siRNA
piRNA
lncRNA
circRNA
url https://www.clinmedkaz.org/download/regulator-non-coding-rnas-mirna-sirna-pirna-lncrna-circrna-9258.pdf
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