A Comparative Study of the Impacts of Aloe vera Gel and Silver Sulfadiazine Cream 1% on Healing, Itching and Pain of Burn Wounds: A Randomized Clinical Trial
Introduction: Although several studies have highlighted the beneficial effects of Aloe vera on burn wounds, limited clinical evidence exists in this regard. This study aimed to evaluate the impact of the Aloe vera gel on healing, itching and pain of burn patients. Methods: This clinical trial was co...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tabriz University of Medical Sciences
2022-08-01
|
| Series: | Journal of Caring Sciences |
| Subjects: | |
| Online Access: | https://jcs.tbzmed.ac.ir/PDF/jcs-11-132.pdf |
| _version_ | 1818517103294021632 |
|---|---|
| author | Maryam Mahboub Ahmad Mirza Aghazadeh Attari Zahra Sheikhalipour Mohammad Mirza Aghazadeh Attari Babak Davami Alireza Amidfar Mojgan Lotfi |
| author_facet | Maryam Mahboub Ahmad Mirza Aghazadeh Attari Zahra Sheikhalipour Mohammad Mirza Aghazadeh Attari Babak Davami Alireza Amidfar Mojgan Lotfi |
| author_sort | Maryam Mahboub |
| collection | DOAJ |
| description | Introduction: Although several studies have highlighted the beneficial effects of Aloe vera on burn wounds, limited clinical evidence exists in this regard. This study aimed to evaluate the impact of the Aloe vera gel on healing, itching and pain of burn patients. Methods: This clinical trial was conducted at Sina Hospital in Tabriz, Iran. The patients with second and first degree burn wounds on symmetrical organs, were randomly assigned to control (n=34) and experimental (n=34) groups. The Aloe vera gel and silver sulfadiazine cream were used in the experimental and control groups, respectively. To assess the healing effects, the Bates-Jensen Wound Assessment Tool (BWAT) was employed. Regarding itching and pain, visual analogue scale (VAS) was used for precise evaluation and comparison on days 1, 3, 5, 7, 9 and 14. The data were analyzed using SPSS version 13. Results: Although the wounds in both groups healed up completely within two weeks, the healing process among the patients in the experimental group was faster. The peak of wound itching was on day 7 in both groups. The wound itching significantly reduced half an hour after being dressed with Aloe vera gel. The wound pain in the experimental group was less than control group during the study period. Moreover, there was no pain in either experimental or control group on day 14. Conclusion: Aloe vera is an effective agent in reducing itching and pain, and it can substantially increase the rate of healing. Accordingly, this agent can be considered in the treatment of burn wounds. |
| first_indexed | 2024-12-11T00:51:42Z |
| format | Article |
| id | doaj.art-f6cf9cb932bd4e5fa7fabbf0217df3ac |
| institution | Directory Open Access Journal |
| issn | 2251-9920 |
| language | English |
| last_indexed | 2024-12-11T00:51:42Z |
| publishDate | 2022-08-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Caring Sciences |
| spelling | doaj.art-f6cf9cb932bd4e5fa7fabbf0217df3ac2022-12-22T01:26:37ZengTabriz University of Medical SciencesJournal of Caring Sciences2251-99202022-08-0111313213810.34172/jcs.2021.036jcs-30306A Comparative Study of the Impacts of Aloe vera Gel and Silver Sulfadiazine Cream 1% on Healing, Itching and Pain of Burn Wounds: A Randomized Clinical TrialMaryam Mahboub0Ahmad Mirza Aghazadeh Attari1Zahra Sheikhalipour2Mohammad Mirza Aghazadeh Attari3Babak Davami4Alireza Amidfar5Mojgan Lotfi6Department of Medical and Surgical Nursing, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Basic Sciences, Faculty of Paramedicine, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Medical and Surgical Nursing, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, IranFaculty of Medicine, Medical Imaging Center, Tabriz University of Medical Sciences, Tabriz, IranPlastic Surgeon, Sina Hospital, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Medical and Surgical Nursing, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Medical and Surgical Nursing, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, IranIntroduction: Although several studies have highlighted the beneficial effects of Aloe vera on burn wounds, limited clinical evidence exists in this regard. This study aimed to evaluate the impact of the Aloe vera gel on healing, itching and pain of burn patients. Methods: This clinical trial was conducted at Sina Hospital in Tabriz, Iran. The patients with second and first degree burn wounds on symmetrical organs, were randomly assigned to control (n=34) and experimental (n=34) groups. The Aloe vera gel and silver sulfadiazine cream were used in the experimental and control groups, respectively. To assess the healing effects, the Bates-Jensen Wound Assessment Tool (BWAT) was employed. Regarding itching and pain, visual analogue scale (VAS) was used for precise evaluation and comparison on days 1, 3, 5, 7, 9 and 14. The data were analyzed using SPSS version 13. Results: Although the wounds in both groups healed up completely within two weeks, the healing process among the patients in the experimental group was faster. The peak of wound itching was on day 7 in both groups. The wound itching significantly reduced half an hour after being dressed with Aloe vera gel. The wound pain in the experimental group was less than control group during the study period. Moreover, there was no pain in either experimental or control group on day 14. Conclusion: Aloe vera is an effective agent in reducing itching and pain, and it can substantially increase the rate of healing. Accordingly, this agent can be considered in the treatment of burn wounds.https://jcs.tbzmed.ac.ir/PDF/jcs-11-132.pdfburnsaloe vera gelwound healingpainitching |
| spellingShingle | Maryam Mahboub Ahmad Mirza Aghazadeh Attari Zahra Sheikhalipour Mohammad Mirza Aghazadeh Attari Babak Davami Alireza Amidfar Mojgan Lotfi A Comparative Study of the Impacts of Aloe vera Gel and Silver Sulfadiazine Cream 1% on Healing, Itching and Pain of Burn Wounds: A Randomized Clinical Trial Journal of Caring Sciences burns aloe vera gel wound healing pain itching |
| title | A Comparative Study of the Impacts of Aloe vera Gel and Silver Sulfadiazine Cream 1% on Healing, Itching and Pain of Burn Wounds: A Randomized Clinical Trial |
| title_full | A Comparative Study of the Impacts of Aloe vera Gel and Silver Sulfadiazine Cream 1% on Healing, Itching and Pain of Burn Wounds: A Randomized Clinical Trial |
| title_fullStr | A Comparative Study of the Impacts of Aloe vera Gel and Silver Sulfadiazine Cream 1% on Healing, Itching and Pain of Burn Wounds: A Randomized Clinical Trial |
| title_full_unstemmed | A Comparative Study of the Impacts of Aloe vera Gel and Silver Sulfadiazine Cream 1% on Healing, Itching and Pain of Burn Wounds: A Randomized Clinical Trial |
| title_short | A Comparative Study of the Impacts of Aloe vera Gel and Silver Sulfadiazine Cream 1% on Healing, Itching and Pain of Burn Wounds: A Randomized Clinical Trial |
| title_sort | comparative study of the impacts of aloe vera gel and silver sulfadiazine cream 1 on healing itching and pain of burn wounds a randomized clinical trial |
| topic | burns aloe vera gel wound healing pain itching |
| url | https://jcs.tbzmed.ac.ir/PDF/jcs-11-132.pdf |
| work_keys_str_mv | AT maryammahboub acomparativestudyoftheimpactsofaloeveragelandsilversulfadiazinecream1onhealingitchingandpainofburnwoundsarandomizedclinicaltrial AT ahmadmirzaaghazadehattari acomparativestudyoftheimpactsofaloeveragelandsilversulfadiazinecream1onhealingitchingandpainofburnwoundsarandomizedclinicaltrial AT zahrasheikhalipour acomparativestudyoftheimpactsofaloeveragelandsilversulfadiazinecream1onhealingitchingandpainofburnwoundsarandomizedclinicaltrial AT mohammadmirzaaghazadehattari acomparativestudyoftheimpactsofaloeveragelandsilversulfadiazinecream1onhealingitchingandpainofburnwoundsarandomizedclinicaltrial AT babakdavami acomparativestudyoftheimpactsofaloeveragelandsilversulfadiazinecream1onhealingitchingandpainofburnwoundsarandomizedclinicaltrial AT alirezaamidfar acomparativestudyoftheimpactsofaloeveragelandsilversulfadiazinecream1onhealingitchingandpainofburnwoundsarandomizedclinicaltrial AT mojganlotfi acomparativestudyoftheimpactsofaloeveragelandsilversulfadiazinecream1onhealingitchingandpainofburnwoundsarandomizedclinicaltrial AT maryammahboub comparativestudyoftheimpactsofaloeveragelandsilversulfadiazinecream1onhealingitchingandpainofburnwoundsarandomizedclinicaltrial AT ahmadmirzaaghazadehattari comparativestudyoftheimpactsofaloeveragelandsilversulfadiazinecream1onhealingitchingandpainofburnwoundsarandomizedclinicaltrial AT zahrasheikhalipour comparativestudyoftheimpactsofaloeveragelandsilversulfadiazinecream1onhealingitchingandpainofburnwoundsarandomizedclinicaltrial AT mohammadmirzaaghazadehattari comparativestudyoftheimpactsofaloeveragelandsilversulfadiazinecream1onhealingitchingandpainofburnwoundsarandomizedclinicaltrial AT babakdavami comparativestudyoftheimpactsofaloeveragelandsilversulfadiazinecream1onhealingitchingandpainofburnwoundsarandomizedclinicaltrial AT alirezaamidfar comparativestudyoftheimpactsofaloeveragelandsilversulfadiazinecream1onhealingitchingandpainofburnwoundsarandomizedclinicaltrial AT mojganlotfi comparativestudyoftheimpactsofaloeveragelandsilversulfadiazinecream1onhealingitchingandpainofburnwoundsarandomizedclinicaltrial |