Polymorphisms and Pharmacogenomics of <i>NQO2</i>: The Past and the Future

Polymorphisms and Pharmacogenomics of <i>NQO2</i>: The Past and the Future

The flavoenzyme N-ribosyldihydronicotinamide (NRH):quinone oxidoreductase 2 (NQO2) catalyzes two-electron reductions of quinones. NQO2 contributes to the metabolism of biogenic and xenobiotic quinones, including a wide range of antitumor drugs, with both toxifying and detoxifying functions. Moreover...

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Bibliographic Details
Main Authors: Elzbieta Janda, Jean A. Boutin, Carlo De Lorenzo, Mariamena Arbitrio
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Genes
Subjects:
NQO2
QR2
SNP
cancer
pharmacogenomics
neurodegenerative disease
Online Access:https://www.mdpi.com/2073-4425/15/1/87

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