In Vitro Antitumor Activity of Stellettin B, a Triterpene from Marine Sponge Jaspis stellifera, on Human Glioblastoma Cancer SF295 Cells

In Vitro Antitumor Activity of Stellettin B, a Triterpene from Marine Sponge Jaspis stellifera, on Human Glioblastoma Cancer SF295 Cells

Stellettin B was isolated from marine sponge Jaspis stellifera. In vitro antitumor activities were investigated on 39 human cancer cell lines. Stellettin B exhibited highly potent inhibition against the growth of a human glioblastoma cell line SF295, with a GI50 of 0.01 μM. In contrast, stellettin B...

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Bibliographic Details
Main Authors: Sheng-An Tang, Qianxiang Zhou, Wen-Zhi Guo, Yuling Qiu, Ran Wang, Meihua Jin, Wenjing Zhang, Ke Li, Takao Yamori, Shingo Dan, Dexin Kong
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Marine Drugs
Subjects:
stellettin B
antitumor activity
apoptosis
p-Akt
in vitro
Online Access:http://www.mdpi.com/1660-3397/12/7/4200

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