The effect of sagittal alignment, coronal balance, and segmental stability on preoperative patient-reported outcomes in patients with degenerative lumbar spondylolisthesis
Abstract Objective The aim of this study was to investigate the association between spinal alignment and preoperative patient-reported outcomes (PROs) in patients with degenerative lumbar spondylolisthesis (DLS) and to identify the independent risk factors for worse preoperative PROs. Methods In tot...
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| Format: | Article |
| Language: | English |
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BMC
2023-03-01
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| Series: | BMC Surgery |
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| Online Access: | https://doi.org/10.1186/s12893-023-01947-2 |
| _version_ | 1827985358871068672 |
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| author | Dong-Fan Wang Xiao-Long Chen Di Han Chao Kong Shi-Bao Lu |
| author_facet | Dong-Fan Wang Xiao-Long Chen Di Han Chao Kong Shi-Bao Lu |
| author_sort | Dong-Fan Wang |
| collection | DOAJ |
| description | Abstract Objective The aim of this study was to investigate the association between spinal alignment and preoperative patient-reported outcomes (PROs) in patients with degenerative lumbar spondylolisthesis (DLS) and to identify the independent risk factors for worse preoperative PROs. Methods In total, 101 patients suffering from DLS were retrospectively studied within a single medical center. Age, sex, height, weight, and body mass index were uniformly recorded. PRO-related indicators include the Oswestry Disability Index (ODI), the Japanese Orthopedic Association’s (JOA) score, and the visual analog scale (VAS) for back and leg pain. Sagittal alignment, coronal balance, and stability of the L4/5 level were evaluated through whole-spine anteroposterior and lateral radiographs and dynamic lumbar X-ray. Results Increasing age (P = 0.005), higher sagittal vertical axis (SVA) (P < 0.001), and global coronal imbalance (GCI) (P = 0.023) were independent risk factors for higher ODI. Patients with GCI had lower JOA scores (P = 0.001) than those with balanced coronal alignment. Unstable spondylolisthesis (P < 0.001) and GCI (P = 0.009) were two vital predictors of VAS-back pain. Increasing age (P = 0.031), local coronal imbalance (LCI) (P < 0.001), and GCI (P < 0.001) were associated with higher VAS-leg pain. Moreover, patients with coronal imbalance also exhibited significant sagittal malalignment based on the subgroup analysis. Conclusion DLS patients with higher SVA, unstable spondylolistheses, a combination of LCI/GCI, or increasing age were predisposed to have more severe subjective symptoms before surgery. |
| first_indexed | 2024-04-09T23:13:38Z |
| format | Article |
| id | doaj.art-f6d50b6a3d8949bca724eddf08e0ee9a |
| institution | Directory Open Access Journal |
| issn | 1471-2482 |
| language | English |
| last_indexed | 2024-04-09T23:13:38Z |
| publishDate | 2023-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Surgery |
| spelling | doaj.art-f6d50b6a3d8949bca724eddf08e0ee9a2023-03-22T10:17:58ZengBMCBMC Surgery1471-24822023-03-0123111110.1186/s12893-023-01947-2The effect of sagittal alignment, coronal balance, and segmental stability on preoperative patient-reported outcomes in patients with degenerative lumbar spondylolisthesisDong-Fan Wang0Xiao-Long Chen1Di Han2Chao Kong3Shi-Bao Lu4Department of Orthopedics, Xuanwu Hospital, Capital Medical UniversityDepartment of Orthopedics, Xuanwu Hospital, Capital Medical UniversityDepartment of Orthopedics, Xuanwu Hospital, Capital Medical UniversityDepartment of Orthopedics, Xuanwu Hospital, Capital Medical UniversityDepartment of Orthopedics, Xuanwu Hospital, Capital Medical UniversityAbstract Objective The aim of this study was to investigate the association between spinal alignment and preoperative patient-reported outcomes (PROs) in patients with degenerative lumbar spondylolisthesis (DLS) and to identify the independent risk factors for worse preoperative PROs. Methods In total, 101 patients suffering from DLS were retrospectively studied within a single medical center. Age, sex, height, weight, and body mass index were uniformly recorded. PRO-related indicators include the Oswestry Disability Index (ODI), the Japanese Orthopedic Association’s (JOA) score, and the visual analog scale (VAS) for back and leg pain. Sagittal alignment, coronal balance, and stability of the L4/5 level were evaluated through whole-spine anteroposterior and lateral radiographs and dynamic lumbar X-ray. Results Increasing age (P = 0.005), higher sagittal vertical axis (SVA) (P < 0.001), and global coronal imbalance (GCI) (P = 0.023) were independent risk factors for higher ODI. Patients with GCI had lower JOA scores (P = 0.001) than those with balanced coronal alignment. Unstable spondylolisthesis (P < 0.001) and GCI (P = 0.009) were two vital predictors of VAS-back pain. Increasing age (P = 0.031), local coronal imbalance (LCI) (P < 0.001), and GCI (P < 0.001) were associated with higher VAS-leg pain. Moreover, patients with coronal imbalance also exhibited significant sagittal malalignment based on the subgroup analysis. Conclusion DLS patients with higher SVA, unstable spondylolistheses, a combination of LCI/GCI, or increasing age were predisposed to have more severe subjective symptoms before surgery.https://doi.org/10.1186/s12893-023-01947-2DegenerativeLumbar spondylolisthesisAlignmentPatient-reported outcomesInfluencing factors |
| spellingShingle | Dong-Fan Wang Xiao-Long Chen Di Han Chao Kong Shi-Bao Lu The effect of sagittal alignment, coronal balance, and segmental stability on preoperative patient-reported outcomes in patients with degenerative lumbar spondylolisthesis BMC Surgery Degenerative Lumbar spondylolisthesis Alignment Patient-reported outcomes Influencing factors |
| title | The effect of sagittal alignment, coronal balance, and segmental stability on preoperative patient-reported outcomes in patients with degenerative lumbar spondylolisthesis |
| title_full | The effect of sagittal alignment, coronal balance, and segmental stability on preoperative patient-reported outcomes in patients with degenerative lumbar spondylolisthesis |
| title_fullStr | The effect of sagittal alignment, coronal balance, and segmental stability on preoperative patient-reported outcomes in patients with degenerative lumbar spondylolisthesis |
| title_full_unstemmed | The effect of sagittal alignment, coronal balance, and segmental stability on preoperative patient-reported outcomes in patients with degenerative lumbar spondylolisthesis |
| title_short | The effect of sagittal alignment, coronal balance, and segmental stability on preoperative patient-reported outcomes in patients with degenerative lumbar spondylolisthesis |
| title_sort | effect of sagittal alignment coronal balance and segmental stability on preoperative patient reported outcomes in patients with degenerative lumbar spondylolisthesis |
| topic | Degenerative Lumbar spondylolisthesis Alignment Patient-reported outcomes Influencing factors |
| url | https://doi.org/10.1186/s12893-023-01947-2 |
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