Impact of Natural Blind Spot Location on Perimetry
Abstract We study the spatial distribution of natural blind spot location (NBSL) and its impact on perimetry. Pattern deviation (PD) values of 11,449 reliable visual fields (VFs) that are defined as clinically unaffected based on summary indices were extracted from 11,449 glaucoma patients. We model...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2017-07-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-017-06580-7 |
| _version_ | 1819040076542246912 |
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| author | Mengyu Wang Lucy Q. Shen Michael V. Boland Sarah R. Wellik Carlos Gustavo De Moraes Jonathan S. Myers Peter J. Bex Tobias Elze |
| author_facet | Mengyu Wang Lucy Q. Shen Michael V. Boland Sarah R. Wellik Carlos Gustavo De Moraes Jonathan S. Myers Peter J. Bex Tobias Elze |
| author_sort | Mengyu Wang |
| collection | DOAJ |
| description | Abstract We study the spatial distribution of natural blind spot location (NBSL) and its impact on perimetry. Pattern deviation (PD) values of 11,449 reliable visual fields (VFs) that are defined as clinically unaffected based on summary indices were extracted from 11,449 glaucoma patients. We modeled NBSL distribution using a two-dimensional non-linear regression approach and correlated NBSL with spherical equivalent (SE). Additionally, we compared PD values of groups with longer and shorter distances than median, and larger and smaller angles than median between NBSL and fixation. Mean and standard deviation of horizontal and vertical NBSL were 14.33° ± 1.37° and −2.06° ± 1.27°, respectively. SE decreased with increasing NBSL (correlation: r = −0.14, p < 0.001). For NBSL distances longer than median distance (14.32°), average PD values decreased in the upper central (average difference for significant points (ADSP): −0.18 dB) and increased in the lower nasal VF region (ADSP: 0.14 dB). For angles in the direction of upper hemifield relative to the median angle (−8.13°), PD values decreased in lower nasal (ADSP: −0.11 dB) and increased in upper temporal VF areas (ADSP: 0.19 dB). In conclusion, we demonstrate that NBSL has a systematic effect on the spatial distribution of VF sensitivity. |
| first_indexed | 2024-12-21T09:03:21Z |
| format | Article |
| id | doaj.art-f6d610b24ba844cfb2f0df8dabd16b8d |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-21T09:03:21Z |
| publishDate | 2017-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-f6d610b24ba844cfb2f0df8dabd16b8d2022-12-21T19:09:25ZengNature PortfolioScientific Reports2045-23222017-07-01711910.1038/s41598-017-06580-7Impact of Natural Blind Spot Location on PerimetryMengyu Wang0Lucy Q. Shen1Michael V. Boland2Sarah R. Wellik3Carlos Gustavo De Moraes4Jonathan S. Myers5Peter J. Bex6Tobias Elze7Schepens Eye Research Institute, Harvard Medical SchoolMass. Eye and Ear Infirmary, Harvard Medical SchoolWilmer Eye Institute, Johns Hopkins University School of MedicineBascom Palmer Eye Institute, University of Miami School of MedicineEdward S. Harkness Eye Institute, Columbia University Medical CenterWills Eye Hospital, Thomas Jefferson UniversityDepartment of Psychology, Northeastern UniversitySchepens Eye Research Institute, Harvard Medical SchoolAbstract We study the spatial distribution of natural blind spot location (NBSL) and its impact on perimetry. Pattern deviation (PD) values of 11,449 reliable visual fields (VFs) that are defined as clinically unaffected based on summary indices were extracted from 11,449 glaucoma patients. We modeled NBSL distribution using a two-dimensional non-linear regression approach and correlated NBSL with spherical equivalent (SE). Additionally, we compared PD values of groups with longer and shorter distances than median, and larger and smaller angles than median between NBSL and fixation. Mean and standard deviation of horizontal and vertical NBSL were 14.33° ± 1.37° and −2.06° ± 1.27°, respectively. SE decreased with increasing NBSL (correlation: r = −0.14, p < 0.001). For NBSL distances longer than median distance (14.32°), average PD values decreased in the upper central (average difference for significant points (ADSP): −0.18 dB) and increased in the lower nasal VF region (ADSP: 0.14 dB). For angles in the direction of upper hemifield relative to the median angle (−8.13°), PD values decreased in lower nasal (ADSP: −0.11 dB) and increased in upper temporal VF areas (ADSP: 0.19 dB). In conclusion, we demonstrate that NBSL has a systematic effect on the spatial distribution of VF sensitivity.https://doi.org/10.1038/s41598-017-06580-7 |
| spellingShingle | Mengyu Wang Lucy Q. Shen Michael V. Boland Sarah R. Wellik Carlos Gustavo De Moraes Jonathan S. Myers Peter J. Bex Tobias Elze Impact of Natural Blind Spot Location on Perimetry Scientific Reports |
| title | Impact of Natural Blind Spot Location on Perimetry |
| title_full | Impact of Natural Blind Spot Location on Perimetry |
| title_fullStr | Impact of Natural Blind Spot Location on Perimetry |
| title_full_unstemmed | Impact of Natural Blind Spot Location on Perimetry |
| title_short | Impact of Natural Blind Spot Location on Perimetry |
| title_sort | impact of natural blind spot location on perimetry |
| url | https://doi.org/10.1038/s41598-017-06580-7 |
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