Uncovering a Genetic Polymorphism Located in Huntingtin Associated Protein 1 in Modulation of Central Pain Sensitization Signaling Pathways

Uncovering a Genetic Polymorphism Located in Huntingtin Associated Protein 1 in Modulation of Central Pain Sensitization Signaling Pathways

Fibromyalgia syndrome (FMS) is characterized by widespread pain and increased sensitivity to nociceptive stimulus or tenderness. While familial aggregation could suggest a potential hereditary component in FMS development, isolation of genetic determinants has proven difficult due to the multi-facto...

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Bibliographic Details
Main Authors: Yvonne Gloor, Alain Matthey, Komla Sobo, Médéric Mouterde, Eva Kosek, Gisèle Pickering, Estella S. Poloni, Christine Cedraschi, Georg Ehret, Jules A. Desmeules
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Neuroscience
Subjects:
central sensitization
nociceptive flection reflex (NFR) threshold
fibromyalgia
GWAS
HAP1
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.807773/full

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https://www.frontiersin.org/articles/10.3389/fnins.2022.807773/full

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