Anti-Toxoplasma gondii effect of lupane-type triterpenes from the bark of black alder (Alnus glutinosa) and identification of a potential target by reverse docking

Anti-Toxoplasma gondii effect of lupane-type triterpenes from the bark of black alder (Alnus glutinosa) and identification of a potential target by reverse docking

Toxoplasmosis is a worldwide parasitosis that is generally benign. The infestation may pose a risk to immunocompromized patients and to fetuses when pregnant women have recently seroconverted. Current treatments have numerous side effects and chemoresistance is emerging, hence the need to find new a...

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Bibliographic Details
Main Authors: Darme Pierre, Escotte-Binet Sandie, Cordonnier Julien, Remy Simon, Hubert Jane, Sayagh Charlotte, Borie Nicolas, Villena Isabelle, Voutquenne-Nazabadioko Laurence, Dauchez Manuel, Baud Stéphanie, Renault Jean-Hugues, Aubert Dominique
Format: Article
Language:English
Published: EDP Sciences 2022-01-01
Series:Parasite
Subjects:
toxoplasma gondii
alnus glutinosa
triterpene
betulone
inverse docking
target hypothesis
Online Access:https://www.parasite-journal.org/articles/parasite/full_html/2022/01/parasite210145/parasite210145.html

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