The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and Disease
The leakage of the intestinal barrier and the disruption of the gut microbiome are increasingly recognized as key factors in different pathophysiological conditions, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), chronic liver diseases, obesity, diabetes mellitus, types of...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-04-01
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| Series: | Frontiers in Nutrition |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2022.718710/full |
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| author | Orsolya Inczefi Péter Bacsur Tamás Resál Csilla Keresztes Tamás Molnár |
| author_facet | Orsolya Inczefi Péter Bacsur Tamás Resál Csilla Keresztes Tamás Molnár |
| author_sort | Orsolya Inczefi |
| collection | DOAJ |
| description | The leakage of the intestinal barrier and the disruption of the gut microbiome are increasingly recognized as key factors in different pathophysiological conditions, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), chronic liver diseases, obesity, diabetes mellitus, types of cancer, and neuropsychiatric disorders. In this study, the mechanisms leading to dysbiosis and “leaky gut” are reviewed, and a short summary of the current knowledge regarding different diseases is provided. The simplest way to restore intestinal permeability and the microbiota could be ideal nutrition. Further therapeutic options are also available, such as the administration of probiotics or postbiotics or fecal microbiota transplantation. |
| first_indexed | 2024-12-10T10:16:34Z |
| format | Article |
| id | doaj.art-f6dbfc612ebc49e28dc72def4d8c9993 |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-12-10T10:16:34Z |
| publishDate | 2022-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-f6dbfc612ebc49e28dc72def4d8c99932022-12-22T01:53:00ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2022-04-01910.3389/fnut.2022.718710718710The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and DiseaseOrsolya Inczefi0Péter Bacsur1Tamás Resál2Csilla Keresztes3Tamás Molnár4Department of Gastroenterology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, HungaryDepartment of Gastroenterology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, HungaryDepartment of Gastroenterology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, HungaryDepartment for Medical Communication and Translation Studies, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, HungaryDepartment of Gastroenterology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, HungaryThe leakage of the intestinal barrier and the disruption of the gut microbiome are increasingly recognized as key factors in different pathophysiological conditions, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), chronic liver diseases, obesity, diabetes mellitus, types of cancer, and neuropsychiatric disorders. In this study, the mechanisms leading to dysbiosis and “leaky gut” are reviewed, and a short summary of the current knowledge regarding different diseases is provided. The simplest way to restore intestinal permeability and the microbiota could be ideal nutrition. Further therapeutic options are also available, such as the administration of probiotics or postbiotics or fecal microbiota transplantation.https://www.frontiersin.org/articles/10.3389/fnut.2022.718710/fullintestinepermeabilitymicrobiomenutritiondiseaseleaky gut |
| spellingShingle | Orsolya Inczefi Péter Bacsur Tamás Resál Csilla Keresztes Tamás Molnár The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and Disease Frontiers in Nutrition intestine permeability microbiome nutrition disease leaky gut |
| title | The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and Disease |
| title_full | The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and Disease |
| title_fullStr | The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and Disease |
| title_full_unstemmed | The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and Disease |
| title_short | The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and Disease |
| title_sort | influence of nutrition on intestinal permeability and the microbiome in health and disease |
| topic | intestine permeability microbiome nutrition disease leaky gut |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2022.718710/full |
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