Recent Advances and Perspectives in Relation to the Metabolomics-Based Study of Diabetic Retinopathy
Diabetic retinopathy (DR), a prevalent microvascular complication of diabetes, is a major cause of acquired blindness in adults. Currently, a clinical diagnosis of DR primarily relies on fundus fluorescein angiography, with a limited availability of effective biomarkers. Metabolomics, a discipline d...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-09-01
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| Series: | Metabolites |
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| Online Access: | https://www.mdpi.com/2218-1989/13/9/1007 |
| _version_ | 1797578920743141376 |
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| author | Shuling He Lvyun Sun Jiali Chen Yang Ouyang |
| author_facet | Shuling He Lvyun Sun Jiali Chen Yang Ouyang |
| author_sort | Shuling He |
| collection | DOAJ |
| description | Diabetic retinopathy (DR), a prevalent microvascular complication of diabetes, is a major cause of acquired blindness in adults. Currently, a clinical diagnosis of DR primarily relies on fundus fluorescein angiography, with a limited availability of effective biomarkers. Metabolomics, a discipline dedicated to scrutinizing the response of various metabolites within living organisms, has shown noteworthy advancements in uncovering metabolic disorders and identifying key metabolites associated with DR in recent years. Consequently, this review aims to present the latest advancements in metabolomics techniques and comprehensively discuss the principal metabolic outcomes derived from analyzing blood, vitreous humor, aqueous humor, urine, and fecal samples. |
| first_indexed | 2024-03-10T22:28:33Z |
| format | Article |
| id | doaj.art-f6dc55ba711648a0a92e357d34f30b50 |
| institution | Directory Open Access Journal |
| issn | 2218-1989 |
| language | English |
| last_indexed | 2024-03-10T22:28:33Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Metabolites |
| spelling | doaj.art-f6dc55ba711648a0a92e357d34f30b502023-11-19T11:55:28ZengMDPI AGMetabolites2218-19892023-09-01139100710.3390/metabo13091007Recent Advances and Perspectives in Relation to the Metabolomics-Based Study of Diabetic RetinopathyShuling He0Lvyun Sun1Jiali Chen2Yang Ouyang3Department of Health Inspection and Quarantine, School of Public Health, Fujian Medical University, Fuzhou 350122, ChinaDepartment of Health Inspection and Quarantine, School of Public Health, Fujian Medical University, Fuzhou 350122, ChinaDepartment of Health Inspection and Quarantine, School of Public Health, Fujian Medical University, Fuzhou 350122, ChinaDepartment of Health Inspection and Quarantine, School of Public Health, Fujian Medical University, Fuzhou 350122, ChinaDiabetic retinopathy (DR), a prevalent microvascular complication of diabetes, is a major cause of acquired blindness in adults. Currently, a clinical diagnosis of DR primarily relies on fundus fluorescein angiography, with a limited availability of effective biomarkers. Metabolomics, a discipline dedicated to scrutinizing the response of various metabolites within living organisms, has shown noteworthy advancements in uncovering metabolic disorders and identifying key metabolites associated with DR in recent years. Consequently, this review aims to present the latest advancements in metabolomics techniques and comprehensively discuss the principal metabolic outcomes derived from analyzing blood, vitreous humor, aqueous humor, urine, and fecal samples.https://www.mdpi.com/2218-1989/13/9/1007diabetic retinopathymetabolomicsbiomarkermetabolic pathway |
| spellingShingle | Shuling He Lvyun Sun Jiali Chen Yang Ouyang Recent Advances and Perspectives in Relation to the Metabolomics-Based Study of Diabetic Retinopathy Metabolites diabetic retinopathy metabolomics biomarker metabolic pathway |
| title | Recent Advances and Perspectives in Relation to the Metabolomics-Based Study of Diabetic Retinopathy |
| title_full | Recent Advances and Perspectives in Relation to the Metabolomics-Based Study of Diabetic Retinopathy |
| title_fullStr | Recent Advances and Perspectives in Relation to the Metabolomics-Based Study of Diabetic Retinopathy |
| title_full_unstemmed | Recent Advances and Perspectives in Relation to the Metabolomics-Based Study of Diabetic Retinopathy |
| title_short | Recent Advances and Perspectives in Relation to the Metabolomics-Based Study of Diabetic Retinopathy |
| title_sort | recent advances and perspectives in relation to the metabolomics based study of diabetic retinopathy |
| topic | diabetic retinopathy metabolomics biomarker metabolic pathway |
| url | https://www.mdpi.com/2218-1989/13/9/1007 |
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