Adenoviromics: Mining the Human Adenovirus Species D Genome
Human adenovirus (HAdV) infections cause disease world-wide. Whole genome sequencing has now distinguished 90 distinct genotypes in 7 species (A-G). Over half of these 90 HAdVs fall within species D, with essentially all of the HAdV-D whole genome sequences generated in the last decade. Herein, we d...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-09-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fmicb.2018.02178/full |
| _version_ | 1818420270603436032 |
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| author | Ashrafali M. Ismail Ji Sun Lee Jeong Yoon Lee Jeong Yoon Lee Gurdeep Singh Gurdeep Singh David W. Dyer Donald Seto James Chodosh Jaya Rajaiya |
| author_facet | Ashrafali M. Ismail Ji Sun Lee Jeong Yoon Lee Jeong Yoon Lee Gurdeep Singh Gurdeep Singh David W. Dyer Donald Seto James Chodosh Jaya Rajaiya |
| author_sort | Ashrafali M. Ismail |
| collection | DOAJ |
| description | Human adenovirus (HAdV) infections cause disease world-wide. Whole genome sequencing has now distinguished 90 distinct genotypes in 7 species (A-G). Over half of these 90 HAdVs fall within species D, with essentially all of the HAdV-D whole genome sequences generated in the last decade. Herein, we describe recent new findings made possible by mining of this expanded genome database, and propose future directions to elucidate new functional elements and new functions for previously known viral components. |
| first_indexed | 2024-12-14T12:51:48Z |
| format | Article |
| id | doaj.art-f6de00cbefbb41a18bbca5c69a5fe902 |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-12-14T12:51:48Z |
| publishDate | 2018-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-f6de00cbefbb41a18bbca5c69a5fe9022022-12-21T23:00:39ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2018-09-01910.3389/fmicb.2018.02178415096Adenoviromics: Mining the Human Adenovirus Species D GenomeAshrafali M. Ismail0Ji Sun Lee1Jeong Yoon Lee2Jeong Yoon Lee3Gurdeep Singh4Gurdeep Singh5David W. Dyer6Donald Seto7James Chodosh8Jaya Rajaiya9Howe Laboratory, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, United StatesHowe Laboratory, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, United StatesHowe Laboratory, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, United StatesMolecular Virology Laboratory, Korea Zoonosis Research Institute, Jeonbuk National University, Jeonju, South KoreaHowe Laboratory, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, United StatesDepartment of Cell and Systems Biology, University of Toronto, Toronto, ON, CanadaDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United StatesBioinformatics and Computational Biology Program, School of Systems Biology, George Mason University, Manassas, VI, United StatesHowe Laboratory, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, United StatesHowe Laboratory, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, United StatesHuman adenovirus (HAdV) infections cause disease world-wide. Whole genome sequencing has now distinguished 90 distinct genotypes in 7 species (A-G). Over half of these 90 HAdVs fall within species D, with essentially all of the HAdV-D whole genome sequences generated in the last decade. Herein, we describe recent new findings made possible by mining of this expanded genome database, and propose future directions to elucidate new functional elements and new functions for previously known viral components.https://www.frontiersin.org/article/10.3389/fmicb.2018.02178/fulladenovirusgenomeevolutiontranscription factorinteractome |
| spellingShingle | Ashrafali M. Ismail Ji Sun Lee Jeong Yoon Lee Jeong Yoon Lee Gurdeep Singh Gurdeep Singh David W. Dyer Donald Seto James Chodosh Jaya Rajaiya Adenoviromics: Mining the Human Adenovirus Species D Genome Frontiers in Microbiology adenovirus genome evolution transcription factor interactome |
| title | Adenoviromics: Mining the Human Adenovirus Species D Genome |
| title_full | Adenoviromics: Mining the Human Adenovirus Species D Genome |
| title_fullStr | Adenoviromics: Mining the Human Adenovirus Species D Genome |
| title_full_unstemmed | Adenoviromics: Mining the Human Adenovirus Species D Genome |
| title_short | Adenoviromics: Mining the Human Adenovirus Species D Genome |
| title_sort | adenoviromics mining the human adenovirus species d genome |
| topic | adenovirus genome evolution transcription factor interactome |
| url | https://www.frontiersin.org/article/10.3389/fmicb.2018.02178/full |
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